Role of local vitamin D signaling and cellular calcium transport system in bone homeostasis

Vitamin D Receptor in Osteoblasts Is a Negative Regulator of Bone Mass Control

(2013) Yoko Yamamoto et al.   ENDOCRINOLOGY

Villin promoter-mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild-type and vitamin D receptor knockout mice

(2012) Min Cui et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Calcium/calmodulin-signaling supports TRPV4 activation in osteoclasts and regulates bone mass

(2012) Ritsuko Masuyama et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D–induced inhibition of bone mineralization

(2012) Liesbet Lieben et al.   JOURNAL OF CLINICAL INVESTIGATION

Calcemic actions of vitamin D: Effects on the intestine, kidney and bone

(2011) Liesbet Lieben et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Molecular Mechanisms of Calmodulin Action on TRPV5 and Modulation by Parathyroid Hormone

(2011) T. de Groot et al.   MOLECULAR AND CELLULAR BIOLOGY

DominantTRPV4mutations in nonlethal and lethal metatropic dysplasia

(2010) Natalia Camacho et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations

(2010) Hiroshi Kajiya et al.   CELL CALCIUM

Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors

(2010) James C. Fleet et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family

(2010) J. Dai et al.   JOURNAL OF MEDICAL GENETICS

Ca2+-Dependent Desensitization of TRPV2 Channels Is Mediated by Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate

(2010) J. Mercado et al.   JOURNAL OF NEUROSCIENCE

Hyperparathyroidism

(2009) William D Fraser   LANCET

Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C

(2009) Michaela Auer-Grumbach et al.   NATURE GENETICS

Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4

(2009) Han-Xiang Deng et al.   NATURE GENETICS

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

(2009) Guida Landouré et al.   NATURE GENETICS

TRPV4-Mediated Calcium Influx Regulates Terminal Differentiation of Osteoclasts

(2008) Ritsuko Masuyama et al.   Cell Metabolism

Modulation of mouse RANKL gene expression by Runx2 and vitamin D3

(2008) Riko Kitazawa et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia

(2008) Matthew J Rock et al.   NATURE GENETICS

Targeted Deletion of a Distant Transcriptional Enhancer of the Receptor Activator of Nuclear Factor-κB Ligand Gene Reduces Bone Remodeling and Increases Bone Mass

(2007) Carlo Galli et al.   ENDOCRINOLOGY