ONO-5334, a cathepsin K inhibitor, improves bone strength by preferentially increasing cortical bone mass in ovariectomized rats

Intermittent minodronic acid treatment with sufficient bone resorption inhibition prevents reduction in bone mass and strength in ovariectomized rats with established osteopenia comparable with daily treatment

(2013) Aishi Kimoto et al.   BONE

Effects of ONO-5334, a novel orally-active inhibitor of cathepsin K, on bone metabolism

(2011) Yasuo Ochi et al.   BONE

Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey

(2011) Tara Cusick et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys

(2011) C. Jerome et al.   OSTEOPOROSIS INTERNATIONAL

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

(2010) David E. Hughes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Long-term minodronic acid (ONO-5920/YM529) treatment suppresses increased bone turnover, plus prevents reduction in bone mass and bone strength in ovariectomized rats with established osteopenia

(2008) Makoto Tanaka et al.   BONE

Bone density, strength, and formation in adult cathepsin K (−/−) mice

(2008) B. Pennypacker et al.   BONE

The Mechanical Properties of Cancellous Bone in the Proximal Tibia of Ovariectomized Rats

(2006) Harry A. Hogan et al.   JOURNAL OF BONE AND MINERAL RESEARCH