Article
Orthopedics
Amit S. Piple, Jennifer C. Wang, Kareem J. Kebaish, Emily S. Mills, Daniel A. Oakes, Jay R. Lieberman, Alexander B. Christ, Nathanael D. Heckmann
Summary: This study aimed to assess the relationship between prednisone dosage and rates of periprosthetic joint infection (PJI) following total joint arthroplasty (TJA). The study found that patients receiving prednisone therapy were at increased risk of PJI and sepsis, but no dose-dependent relationship between prednisone and infectious complications was identified.
JOURNAL OF ARTHROPLASTY
(2023)
Review
Medicine, General & Internal
Christos Koutserimpas, Symeon Naoum, Vasileios Giovanoulis, Konstantinos Raptis, Kalliopi Alpantaki, Konstantinos Dretakis, Georgia Vrioni, George Samonis
Summary: Fungal hip prosthetic joint infections (PJIs) are rare but severe infections. This review analyzed all published cases of fungal hip PJIs to provide comprehensive information on demographics, causative fungi, treatment options, and infection outcomes.
Article
Medicine, General & Internal
Christopher W. Day, Kerry Costi, Susan Pannach, Gerald J. Atkins, Jochen G. Hofstaetter, Stuart A. Callary, Renjy Nelson, Donald W. Howie, Lucian B. Solomon
Summary: This study aimed to evaluate the effect of staged revision surgery on the rate of infection resolution and the functional outcomes and mortality rate at ten years for patients with periprosthetic joint infection (PJI). The results showed that most patients achieved infection resolution after multiple surgeries, with improved functional outcomes and pain. However, the ten-year mortality rate was higher than that of the general population.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Fu-Yuan Pai, Wei-Lin Chang, Shang-Wen Tsai, Cheng-Fong Chen, Po-Kuei Wu, Wei-Ming Chen
Summary: This study aimed to evaluate the impact of VTE prophylaxis on the risk of early postoperative SSC and PJI in a Taiwanese population. The results showed that pharmacological thromboprophylaxis appeared to be a modifiable risk factor for SSC and PJI in the early postoperative period.
SCIENTIFIC REPORTS
(2022)
Article
Orthopedics
Enrico M. Forlenza, E. Bailey Terhune, John D. D. Higgins, Conor Jones, Jeffrey A. Geller, Craig J. Della Valle
Summary: This study aimed to investigate the impact of colonoscopy and endoscopy on the risk of periprosthetic joint infection (PJI) after total joint arthroplasty (TJA). The results showed that undergoing colonoscopy within 2 months after total knee arthroplasty (TKA) and endoscopy within 1 month after total hip arthroplasty (THA) significantly increased the odds of PJI. It is recommended to delay invasive endoscopic procedures for at least 2 months after TKA and 1 month after THA to minimize the risk of PJI.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Nathanael D. Heckmann, Jennifer C. Wang, Amit S. Piple, Glenda A. Marshall, Emily S. Mills, Kevin C. Liu, Jay R. Lieberman, Alexander B. Christ
Summary: This study analyzed the risk of infection in patients undergoing total knee arthroplasty (TKA) and total hip arthroplasty (THA) who received intraoperative dexamethasone. The results showed that intraoperative dexamethasone was associated with a reduced risk of periprosthetic joint infection (PJI) and other complications. Therefore, this study supports the utilization of intraoperative dexamethasone in TKA or THA.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Christopher N. Carender, David E. DeMik, Natalie A. Glass, Nicolas O. Noiseux, Timothy S. Brown, Nicholas A. Bedard
Summary: In patients with BMI >= 40 kg/m(2), extended oral antibiotic prophylaxis after primary THA and TICS did not reduce rates of wound complications or early PJI.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Infectious Diseases
Mingwei Hu, Yifan Zhang, Xue Yang, Yingzhen Wang, Hao Xu, Shuai Xiang
Summary: Intra-articular administration of vancomycin after arthrotomy closure in total joint arthroplasty can effectively lower the risk of acute postoperative periprosthetic joint infection without increasing the risk of aseptic wound complication or vancomycin-associated systemic toxicity.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Wen-Chi Su, Yu-Chin Lai, Cheng-Hung Lee, Cheng-Min Shih, Chao-Ping Chen, Li-Ling Hung, Shun-Ping Wang
Summary: This study aimed to investigate the effectiveness of preoperative bathing with chlorhexidine gluconate in reducing postoperative periprosthetic joint infection (PJI) rates after total hip arthroplasty (THA). The study included 933 primary THA patients, with no statistically significant differences in age, sex, or operated side between the group that underwent chlorhexidine bathing and the control group. While PJI cases were more common in the control group, the difference was not statistically significant.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Orthopedics
David Kugelman, Mackenzie Roof, Alexander Egol, Isabella Guanche, Antonia F. Chen, Ran Schwarzkopf, Vinay K. Aggarwal
Summary: This study compared the outcomes of real-component (RC) and all-cement (AC) articulating spacers for total hip arthroplasty (THA) periprosthetic joint infection (PJI) treatment. The RC group showed shorter hospital stays and higher likelihood of being discharged home compared to the AC group, with no significant differences in reinfection and reoperation rates between the two spacer constructs.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Jesus M. Villa, Tejbir S. Pannu, Ibrahim Theeb, Martin A. Buttaro, Jose Onativia, Lisandro Carbo, Daniel H. Rienzi, Jose Fregeiro, Nikolai N. Kornilov, Svetlana A. Bozhkova, Nemandra A. Sandiford, Nicolas S. Piuzzi, Carlos A. Higuera, Daniel O. Kendoff
Summary: The most common pathogens for periprosthetic joint infections were Staphylococcus aureus and Staphylococcus epidermidis. The US and the UK had the lowest rates of resistant organisms, while Germany and Russia had the highest. The UK and Uruguay had the lowest rates of polymicrobial infections.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Infectious Diseases
Rory W. Metcalf, Taylor Rowe, Megan Tersteeg, Malcolm E. Dombrowski, Susan Odum, Jesse E. Otero
Summary: This study aimed to investigate the differences in outcomes following revision for chronic periprosthetic joint infection (PJI) between males and females. The results showed no significant relationship between sex and the outcomes of PJI revision.
Article
Orthopedics
Nicholas M. Hernandez, Michael W. Buchanan, Thorsten M. Seyler, Samuel S. Wellman, Jessica Seidelman, William A. Jiranek
Summary: 1.5-stage exchange arthroplasty may be a reasonable method to treat TKA PJI. At a mean follow-up of 2.7 years, there was an acceptable rate of infection recurrence and implant durability.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Jeremy A. Dubin, Zhongming Chen, Sandeep S. Bains, Daniel Hameed, Michael A. Mont, Ronald E. Delanois, James Nace
Summary: This study found that a delay in total hip arthroplasty (THA) after septic arthritis is necessary to reduce the risk of post-THA periprosthetic joint infections (PJI). Patients who underwent THA within 0-6 months and 6-12 months after the diagnosis of septic arthritis had a 38 times and 22 times increased risk of post-THA PJI, respectively, compared to patients without a history of septic arthritis. Diabetes mellitus, obesity, and tobacco use were identified as risk factors for PJI in patients with a history of septic arthritis.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Peter Brumat, Blaz Mavcic, Izak Jurcic, Rihard Trebse
Summary: This study aimed to identify clinical and laboratory predictors for low- and high-grade prosthetic joint infection (PJI) within the first postoperative days following primary total hip/knee arthroplasty (THA/TKA). The results showed that persistent wound drainage (PWD) and leukocyte count product were associated with the risk of infection in different PJI groups.
INTERNATIONAL ORTHOPAEDICS
(2023)