Ursolic acid stimulates UCP2 expression and protects H9c2 cells from hypoxia-reoxygenation injury via p38 signaling

Ursolic acid (UA): A metabolite with promising therapeutic potential

(2016) Dharambir Kashyap et al.   LIFE SCIENCES

Distinct mPTP activation mechanisms in ischaemia–reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphate

(2015) Lea K. Seidlmayer et al.   CARDIOVASCULAR RESEARCH

Berberine was neuroprotective against an in vitro model of brain ischemia: Survival and apoptosis pathways involved

(2014) Elisa Nicoloso Simões Pires et al.   BRAIN RESEARCH

Salidroside and tyrosol from Rhodiola protect H9c2 cells from ischemia/reperfusion-induced apoptosis

(2012) Liwei Sun et al.   LIFE SCIENCES

Quantification of Uncoupling Protein 2 Reveals Its Main Expression in Immune Cells and Selective Up-Regulation during T-Cell Proliferation

(2012) Anne Rupprecht et al.   PLoS One

Highly sensitive and selective pre-column derivatization high-performance liquid chromatography approach for rapid determination of triterpenes oleanolic and ursolic acids and application to Swertia species: Optimization of triterpenic acids extraction and pre-column derivatization using response surface methodology

(2011) Guoliang Li et al.   ANALYTICA CHIMICA ACTA

Protective effects of ligustrazine on TNF-α-induced endothelial dysfunction

(2011) Hong-Jin Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ursolic acid attenuates lipopolysaccharide-induced cognitive deficits in mouse brain through suppressing p38/NF-κB mediated inflammatory pathways

(2011) Yong-Jian Wang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

(2011) Vanniarajan Ayyasamy et al.   PLoS One

Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism

(2011) Sabrina Diano et al.   TRENDS IN MOLECULAR MEDICINE

Protective Effect of Ursolic Acid from Cornus officinalis on the Hydrogen Peroxide-Induced Damage of HEI-OC1 Auditory Cells

(2009) Hyeon-Hee Yu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Autophagy in Ischemic Heart Disease

(2009) Åsa B. Gustafsson et al.   CIRCULATION RESEARCH

Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro

(2009) Jae Ju Jeong et al.   FOOD AND CHEMICAL TOXICOLOGY

Leptin attenuates hypoxia/reoxygenation-induced activation of the intrinsic pathway of apoptosis in rat H9c2 cells

(2009) Eyun-Jung Shin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Antioxidative and Anti-Inflammatory Protection of Oleanolic Acid and Ursolic Acid in PC12 Cells

(2008) Shih-Jei Tsai et al.   JOURNAL OF FOOD SCIENCE

Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice

(2008) Fatiha Moukdar et al.   JOURNAL OF LIPID RESEARCH

Ursolic acid: An anti- and pro-inflammatory triterpenoid

(2008) Yasutaka Ikeda et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2

(2007) Denis Selimovic et al.   CELLULAR SIGNALLING