Metabolic engineering of chloroplasts for artemisinic acid biosynthesis and impact on plant growth

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Efficient metabolic pathway engineering in transgenic tobacco and tomato plastids with synthetic multigene operons

(2013) Y. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin

(2012) François Lévesque et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Experimental Reconstruction of the Functional Transfer of Intron- Containing Plastid Genes to the Nucleus

(2012) Ignacia Fuentes et al.   CURRENT BIOLOGY

Remodeling the isoprenoid pathway in tobacco by expressing the cytoplasmic mevalonate pathway in chloroplasts

(2011) Shashi Kumar et al.   METABOLIC ENGINEERING

Generation of the potent anti-malarial drug artemisinin in tobacco

(2011) Moran Farhi et al.   NATURE BIOTECHNOLOGY

Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptide

(2010) Diane Boyhan et al.   PLANT BIOTECHNOLOGY JOURNAL

Nicotiana benthamiana as a Production Platform for Artemisinin Precursors

(2010) Teun W. J. M. van Herpen et al.   PLoS One

Correlations between RNA and protein expression profiles in 23 human cell lines

(2009) Marcus Gry et al.   BMC GENOMICS

The Molecular Cloning of Artemisinic Aldehyde Δ11(13) Reductase and Its Role in Glandular Trichome-dependent Biosynthesis of Artemisinin inArtemisia annua

(2008) Yansheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

(2008) Jennifer R. Anthony et al.   METABOLIC ENGINEERING

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE