Side-effects of protein kinase inhibitors on ion channels

Bosutinib is active in chronic phase chronic myeloid leukemia after imatinib and dasatinib and/or nilotinib therapy failure

(2012) H. J. Khoury et al.   BLOOD

Protein kinase C, an elusive therapeutic target?

(2012) Daria Mochly-Rosen et al.   NATURE REVIEWS DRUG DISCOVERY

Inhibition of Kv4.3 by genistein via a tyrosine phosphorylation-independent mechanism

(2010) Hee Jae Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Tyrosine kinase-independent inhibition by genistein on spermatogenic T-type calcium channels attenuates mouse sperm motility and acrosome reaction

(2008) Jin Tao et al.   CELL CALCIUM

Unknown

(2008) A. Klose et al.   MOLECULAR PHARMACOLOGY

Genistein inhibits voltage-gated sodium currents in SCG neurons through protein tyrosine kinase-dependent and kinase-independent mechanisms

(2008) Zhanfeng Jia et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The effect of tyrosine kinase inhibitor genistein on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells

(2008) Eun A. Ko et al.   VASCULAR PHARMACOLOGY