Conformational dynamics of full-length inducible human Hsp70 derived from microsecond molecular dynamics simulations in explicit solvent

The C-terminal Helices of Heat Shock Protein 70 Are Essential for J-domain Binding and ATPase Activation

(2012) Xue-Chao Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simulation of the Opening and Closing of Hsp70 Chaperones by Coarse-Grained Molecular Dynamics

(2012) Ewa Gołaś et al.   Journal of Chemical Theory and Computation

Nucleotide-dependent mechanism of Get3 as elucidated from free energy calculations

(2012) J. Wereszczynski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptides and Aptamers Targeting HSP70: A Novel Approach for Anticancer Chemotherapy

(2011) Anne-Laure Rérole et al.   CANCER RESEARCH

Targeting Heat Shock Proteins 70/90 and Proteasome for Cancer Therapy

(2011) R. E. Wang   CURRENT MEDICINAL CHEMISTRY

The effect of Brownian motion of fluorescent probes on measuring nanoscale distances by Förster resonance energy transfer

(2011) Daniel Badali et al.   JOURNAL OF CHEMICAL PHYSICS

The Four Hydrophobic Residues on the Hsp70 Inter-Domain Linker Have Two Distinct Roles

(2011) Divya Prasanna Kumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

(2011) Moritz Marcinowski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanics of Hsp70 chaperones enables differential interaction with client proteins

(2011) Rainer Schlecht et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Heterogeneity and Quantitative FRET Efficiency Distributions of Polyprolines through a Hybrid Atomistic Simulation and Monte Carlo Approach

(2011) Martin Hoefling et al.   PLoS One

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

(2011) A. Zhuravleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Inducible Hsp70: Structures, Dynamics, and Interdomain Communication from All-Atom Molecular Dynamics Simulations

(2010) Adrien Nicolaï et al.   Journal of Chemical Theory and Computation

The Conformational Dynamics of the Mitochondrial Hsp70 Chaperone

(2010) Koyeli Mapa et al.   MOLECULAR CELL

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Single-molecule FRET–derived model of the synaptotagmin 1–SNARE fusion complex

(2010) Ucheor B Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody

(2010) S. Stangl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C-Terminal BAG Domain of BAG5 Induces Conformational Changes of the Hsp70 Nucleotide- Binding Domain for ADP-ATP Exchange

(2010) Akihiko Arakawa et al.   STRUCTURE

The role of molecular chaperones in human misfolding diseases

(2009) Sarah A. Broadley et al.   FEBS LETTERS

Allostery in Hsp70 Chaperones Is Transduced by Subdomain Rotations

(2009) Akash Bhattacharya et al.   JOURNAL OF MOLECULAR BIOLOGY

Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

(2009) E. B. Bertelsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simulation of Structure, Orientation, and Energy Transfer between AlexaFluor Molecules Attached to MscL

(2008) Ben Corry et al.   BIOPHYSICAL JOURNAL

Chaperone machines in action

(2008) Helen R Saibil   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine

(2008) Jonathan P. Schuermann et al.   MOLECULAR CELL

How main-chains of proteins explore the free-energy landscape in native states

(2008) P. Senet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metadynamics: a method to simulate rare events and reconstruct the free energy in biophysics, chemistry and material science

(2008) Alessandro Laio et al.   REPORTS ON PROGRESS IN PHYSICS