Computational Evidence to Inhibition of Human Acetyl Cholinesterase by Withanolide A for Alzheimer Treatment

Hsp90/Cdc37 Chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A

(2011) Abhinav Grover et al.   BMC BIOINFORMATICS

Cholinergic therapy in dementia

(2010) P. J. Whitehouse   ACTA NEUROLOGICA SCANDINAVICA

Blocking the chaperone kinome pathway: Mechanistic insights into a novel dual inhibition approach for supra-additive suppression of malignant tumors

(2010) Abhinav Grover et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes

(2010) Abhinav Grover et al.   BMC GENOMICS

Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera’s key metabolite withaferin A

(2010) Abhinav Grover et al.   BMC GENOMICS

Withanolide A and Asiatic Acid Modulate Multiple Targets Associated with Amyloid-β Precursor Protein Processing and Amyloid-β Protein Clearance

(2010) Sachin P. Patil et al.   JOURNAL OF NATURAL PRODUCTS

In vitro protective effects of Withania somnifera (L.) dunal root extract against hydrogen peroxide and β-amyloid(1-42)-induced cytotoxicity in differentiated PC12 cells

(2010) S. Kumar et al.   PHYTOTHERAPY RESEARCH

Possible Neuroprotective Effect of Withania somnifera Root Extract Against 3-Nitropropionic Acid-Induced Behavioral, Biochemical, and Mitochondrial Dysfunction in an Animal Model of Huntington's Disease

(2009) Puneet Kumar et al.   JOURNAL OF MEDICINAL FOOD

Molecular interactions of cholinesterases inhibitors using in silico methods: current status and future prospects

(2009) Mahmud Tareq Hassan Khan   New Biotechnology

Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors

(2008) Stefania Butini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Overcoming Several Neurodegenerative Diseases by Traditional Medicines

(2008) Chihiro TOHDA   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN