A Novel Strategy for Designing the Selective PPAR Agonist by the “Sum of Activity” Model

Homology Modeling of Wild-type, D516V, and H526LMycobacterium TuberculosisRNA Polymerase and Their Molecular Docking Study with Inhibitors

(2012) Daniela Josa et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Molecular Dynamics, Flexible Docking, Virtual Screening, ADMET Predictions, and Molecular Interaction Field Studies to Design Novel Potential MAO-B Inhibitors

(2012) Glaucia H. Braun et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Reconstructing Potentials of Mean Force from Short Steered Molecular Dynamics Simulations of Vpu from HIV-1

(2012) George Patargias et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Molecular Dynamics Simulations to Gain Insights into the Stability and Morphologies of K3 Oligomers from β2-microglobulin

(2012) Po-Sheng Fang et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Disruption Mechanism in the Helix of SPF Peptide by Interchanging E5 and K10 Residues: Inference from Molecular Dynamics Study

(2012) P. N. Sunilkumar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Homology Modeling of GLUT4, an Insulin Regulated Facilitated Glucose Transporter and Docking Studies with ATP and its Inhibitors

(2012) S. Suma Mohan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Molecular Dynamics Simulations to Investigate the Structural Stability and Aggregation Behavior of the GGVVIA Oligomers Derived from Amyloid β Peptide

(2012) Liang-Kai Chang et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

A Docking Study Using Atomistic Conformers Generated via Elastic Network Model for Cyclosporin A/Cyclophilin A Complex

(2012) E. Demet Akten et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

An Insight to the Dynamics of Conserved Water Molecular Triad in IMPDH II (Human): Recognition of Cofactor and Substrate to Catalytic Arg 322

(2012) Hridoy R. Bairagya et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Structural Rearrangements of Rhodopsin Subunits in a Dimer Complex: a Molecular Dynamics Simulation Study

(2012) Arnau Cordomí et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Construction and Assessment of Reaction Models of Class I EPSP Synthase: Molecular Docking and Density Functional Theoretical Calculations

(2012) Teodorico C. Ramalho et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Studies on the Structural Stability of Rabbit Prion Probed by Molecular Dynamics Simulations

(2012) Jiapu Zhang   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Ligand-Based Dual Target Drug Design for H1N1: Swine Flu- A Preliminary First Study

(2012) Chien-Yu Chen et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Investigation of the Effect of Glycosylation on Human Prion Protein by Molecular Dynamics

(2012) Linghao Zhong et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Molecular Dynamics Simulations to Investigate the Aggregation Behaviors of the Aß(17–42) Oligomers

(2012) Jian-Hua Zhao et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

7-Chloroarctinone-b as a new selective PPARγ antagonist potently blocks adipocyte differentiation

(2009) Yong-tao Li et al.   ACTA PHARMACOLOGICA SINICA

Functional Genomic Analysis Identified Epidermal Growth Factor Receptor Activation as the Most Common Genetic Event in Oral Squamous Cell Carcinoma

(2009) J. J.-C. Sheu et al.   CANCER RESEARCH

Fatty Acid Synthesis and PPARα Hand in Hand

(2009) Nicolas Rotman et al.   CHEMISTRY & BIOLOGY

Ligand-Activated Peroxisome Proliferator–Activated Receptor-γ Protects Against Ischemic Cerebral Infarction and Neuronal Apoptosis by 14-3-3ε Upregulation

(2009) Jui-Sheng Wu et al.   CIRCULATION

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5

(2009) Calvin Yu-Chian Chen   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Pharmacoinformatics approach for mPGES-1 in anti-inflammation by 3D-QSAR pharmacophore mapping

(2009) Calvin Yu-Chian Chen   Journal of the Taiwan Institute of Chemical Engineers

De novo design of novel selective COX-2 inhibitors: From virtual screening to pharmacophore analysis

(2009) Calvin Yu-Chian Chen   Journal of the Taiwan Institute of Chemical Engineers

Chemoinformatics and pharmacoinformatics approach for exploring the GABA-A agonist from Chinese herb suanzaoren

(2009) Calvin Yu-Chian Chen   Journal of the Taiwan Institute of Chemical Engineers

Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)

(2009) Carmen Aceves et al.   Molecular Cancer

Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease

(2009) Emma Robinson et al.   PHARMACOLOGY & THERAPEUTICS

The Medical Risks of Obesity

(2009) Xavier Pi-Sunyer   POSTGRADUATE MEDICINE

Puerariae radix isoflavones and their metabolites inhibit growth and induce apoptosis in breast cancer cells

(2008) Ying-Ju Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Down-regulation of Myeloid Cell Leukemia-1 through Inhibiting Erk/Pin 1 Pathway by Sorafenib Facilitates Chemosensitization in Breast Cancer

(2008) Q. Ding et al.   CANCER RESEARCH

PPAR Modulators and PPAR Pan Agonists for Metabolic Diseases: The Next Generation of Drugs Targeting Peroxisome Proliferator-Activated Receptors?

(2008) P. Feldman et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

‘Sum of activities’ as dependent parameter: A new CoMFA-based approach for the design of pan PPAR agonists

(2008) Sandeep Sundriyal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

PPAR-β/δ agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home

(2008) Andrew N Billin   EXPERT OPINION ON INVESTIGATIONAL DRUGS

PPARδ is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer

(2008) Mallika Ghosh et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS