Modulation of Tight Junction Structure and Function by Kinases and Phosphatases Targeting Occludin

ERK is involved in EGF-mediated protection of tight junctions, but not adherens junctions, in acetaldehyde-treated Caco-2 cell monolayers

(2011) G. Samak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tight Junction Pore and Leak Pathways: A Dynamic Duo

(2011) Le Shen et al.   Annual Review of Physiology

Pathobiology of Junctional Adhesion Molecules

(2011) Gianfranco Bazzoni   ANTIOXIDANTS & REDOX SIGNALING

Occludin Protein Family: Oxidative Stress and Reducing Conditions

(2011) Ingolf E. Blasig et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein kinase Cζ phosphorylates occludin and promotes assembly of epithelial tight junctions

(2011) Suneet Jain et al.   BIOCHEMICAL JOURNAL

c-Yes regulates cell adhesion at the blood–testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes☆

(2011) Xiang Xiao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

AMP-activated Protein Kinase (AMPK) Activation and Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Induce Ca2+-independent Deposition of Tight Junction Components at the Plasma Membrane

(2011) Li Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function

(2011) David R. Raleigh et al.   JOURNAL OF CELL BIOLOGY

LSR defines cell corners for tricellular tight junction formation in epithelial cells

(2011) S. Masuda et al.   JOURNAL OF CELL SCIENCE

Focal Adhesion Kinase Regulation of Mechanotransduction and its Impact on Endothelial Cell Functions

(2011) Noureddine Zebda et al.   MICROVASCULAR RESEARCH

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

(2011) Sònia Tugues et al.   MOLECULAR ASPECTS OF MEDICINE

Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

(2011) Stephen J. Terry et al.   NATURE CELL BIOLOGY

c-Jun NH2-terminal kinase-2 mediates osmotic stress-induced tight junction disruption in the intestinal epithelium

(2010) G. Samak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Contrasting effects of ERK on tight junction integrity in differentiated and under-differentiated Caco-2 cell monolayers

(2010) Sudhir Aggarwal et al.   BIOCHEMICAL JOURNAL

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Tricellulin forms homomeric and heteromeric tight junctional complexes

(2010) Julie K. Westphal et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

(2010) Mutsuki Amano et al.   Cytoskeleton

The Tight Junction Protein, Occludin, Regulates the Directional Migration of Epithelial Cells

(2010) Dan Du et al.   DEVELOPMENTAL CELL

Hypoglycosylated E-cadherin promotes the assembly of tight junctions through the recruitment of PP2A to adherens junctions

(2010) Mihai Nita-Lazar et al.   EXPERIMENTAL CELL RESEARCH

Casein kinase 1: Complexity in the family

(2010) Jit Kong Cheong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

(2010) Amanda M. Marchiando et al.   JOURNAL OF CELL BIOLOGY

Occludin is required for cytokine-induced regulation of tight junction barriers

(2010) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions

(2010) David R. Raleigh et al.   MOLECULAR BIOLOGY OF THE CELL

Differential Phosphorylation of Occludin and Tricellulin by CK2 and CK1

(2009) Max J. Dörfel et al.   Annals of the New York Academy of Sciences

Two-Path Impedance Spectroscopy for Measuring Paracellular and Transcellular Epithelial Resistance

(2009) Susanne M. Krug et al.   BIOPHYSICAL JOURNAL

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family

(2009) Emily Steed et al.   BMC CELL BIOLOGY

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Redox-sensitivity of the dimerization of occludin

(2009) J. K. Walter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) N. A. St-Denis et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) O. Filhol et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells

(2009) Michelle L. Hermiston et al.   IMMUNOLOGICAL REVIEWS

Occludin Phosphorylation and Ubiquitination Regulate Tight Junction Trafficking and Vascular Endothelial Growth Factor-induced Permeability

(2009) Tomoaki Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Density-enhanced Phosphatase 1 Regulates Phosphorylation of Tight Junction Proteins and Enhances Barrier Function of Epithelial Cells

(2009) Jennifer L. Sallee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Analysis of Occludin Phosphosites: A Combined Mass Spectrometry and Bioinformatics Approach

(2009) Jeffrey M. Sundstrom et al.   JOURNAL OF PROTEOME RESEARCH

Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability

(2009) Susanne M. Krug et al.   MOLECULAR BIOLOGY OF THE CELL

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

Focal adhesion kinase is a blood-testis barrier regulator

(2009) E. R. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells

(2008) Masaru Yamamoto et al.   AMERICAN JOURNAL OF PATHOLOGY

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

PI3Kγ controls oxidative bursts in neutrophils via interactions with PKCα and p47phox

(2008) Katja Lehmann et al.   BIOCHEMICAL JOURNAL

Cytokine regulation of tight junctions

(2008) Christopher T. Capaldo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phosphorylation of Tyr-398 and Tyr-402 in Occludin Prevents Its Interaction with ZO-1 and Destabilizes Its Assembly at the Tight Junctions

(2008) Bertha C. Elias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early Embryonic Lethality of Mice Lacking ZO-2, but Not ZO-3, Reveals Critical and Nonredundant Roles for Individual Zonula Occludens Proteins in Mammalian Development

(2008) J. Xu et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of Occludin Affects Tricellular Localization of Tricellulin

(2008) Junichi Ikenouchi et al.   MOLECULAR BIOLOGY OF THE CELL

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS

PKC  regulates occludin phosphorylation and epithelial tight junction integrity

(2008) T. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and function of claudins

(2007) Gerd Krause et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The cytoplasmic plaque of tight junctions: A scaffolding and signalling center

(2007) Laurent Guillemot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES