Ustekinumab in Psoriasis Immunopathology with Emphasis on the Th17-IL23 Axis: A Primer

New Interleukin-23 Pathway Inhibitors in Dermatology

(2011) Marta Kurzeja et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives

(2011) Newman Yeilding et al.   Annals of the New York Academy of Sciences

TH1, TH2, and TH17 cells instruct monocytes to differentiate into specialized dendritic cell subsets

(2011) M. N. Alonso et al.   BLOOD

Ustekinumab

(2011) Jamie D. Croxtall   DRUGS

Ustekinumab for Rapid Treatment of Nail Psoriasis

(2010) Efstathios Rallis et al.   ARCHIVES OF DERMATOLOGY

The use of ustekinumab in autoimmune disease

(2010) Caitriona Ryan et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The therapeutic potential of TNF-α antagonists for skin psoriasis comorbidities

(2010) Gérald E Piérard et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab

(2010) Jinquan Luo et al.   JOURNAL OF MOLECULAR BIOLOGY

New Insights in the Immunologic Basis of Psoriasis

(2010) Kristine E. Nograles et al.   SEMINARS IN CUTANEOUS MEDICINE AND SURGERY

Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

(2010) Kamini Shah et al.   ARTHRITIS RESEARCH & THERAPY

Th17/Tc17 infiltration and associated cytokine gene expression in elicitation phase of allergic contact dermatitis

(2009) Y. Zhao et al.   BRITISH JOURNAL OF DERMATOLOGY

Cytokine gene-mediated immunotherapy: Current status and future perspectives

(2009) Masahisa Jinushi et al.   CANCER SCIENCE

Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

(2009) Lyudmila Lyakh et al.   IMMUNOLOGICAL REVIEWS

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

(2009) Lisa C. Zaba et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased expression of IL-12p70 and IL-23 by multiple dendritic cell and macrophage subsets in plaque psoriasis

(2009) Nikhil Yawalkar et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Efficacy of ABT-874, a Fully Human Interleukin 12/23 Monoclonal Antibody, in the Treatment of Moderate to Severe Chronic Plaque Psoriasis

(2008) Alexa B. Kimball   ARCHIVES OF DERMATOLOGY

Increased expression of interleukin-23 p19 mRNA in erythema nodosum-like lesions of Behçet’s disease

(2008) W. Lew et al.   BRITISH JOURNAL OF DERMATOLOGY

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways

(2008) K.E. Nograles et al.   BRITISH JOURNAL OF DERMATOLOGY

Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity

(2008) Chun Kwok Wong et al.   CLINICAL IMMUNOLOGY

Th17 cells: a new fate for differentiating helper T cells

(2008) Zhi Chen et al.   IMMUNOLOGIC RESEARCH

IL-23 and TH17-mediated inflammation in human allergic contact dermatitis

(2008) Jeppe Madura Larsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th17 cells: A new therapeutic target in inflammatory dermatoses

(2008) Adam Asarch et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Th17 cells: A new paradigm for cutaneous inflammation

(2008) Adam Asarch et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

(2008) Michelle A. Lowes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2008) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

(2008) Craig L Leonardi et al.   LANCET

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE