Elongator: An Ancestral Complex Driving Transcription and Migration through Protein Acetylation

A role for the elongator complex in zygotic paternal genome demethylation

(2010) Yuki Okada et al.   NATURE

MEC-17 is an α-tubulin acetyltransferase

(2010) Jyothi S. Akella et al.   NATURE

Plant Elongator regulates auxin-related genes during RNA polymerase II transcription elongation

(2010) H. Nelissen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Caenorhabditis elegans Elongator Complex Regulates Neuronal α-tubulin Acetylation

(2010) Jachen A. Solinger et al.   PLoS Genetics

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4

(2009) Constance Mehlgarten et al.   MOLECULAR MICROBIOLOGY

Identification of an RNA-dependent RNA polymerase in Drosophila involved in RNAi and transposon suppression

(2009) C. Lipardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elongator – an emerging role in neurological disorders

(2009) Laurent Nguyen et al.   TRENDS IN MOLECULAR MEDICINE

The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents

(2009) Qing Li et al.   PLoS Genetics

Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells

(2008) Isabelle Cornez et al.   BIOCHEMICAL PHARMACOLOGY

Tubulin modifications and their cellular functions

(2008) Jennetta W Hammond et al.   CURRENT OPINION IN CELL BIOLOGY

Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration

(2008) Claire L. Simpson et al.   HUMAN MOLECULAR GENETICS

An Iron-Sulfur Cluster Domain in Elp3 Important for the Structural Integrity of Elongator

(2008) Catherine Greenwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP

(2008) Y.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY