A Window into the Heterogeneity of Human Cerebrospinal Fluid AβPeptides

Novel T719P AβPP Mutation Unbalances the Relative Proportion of Amyloid-β Peptides

(2017) Roberta Ghidoni et al.   JOURNAL OF ALZHEIMERS DISEASE

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

Improving CSF biomarker accuracy in predicting prevalent and incident Alzheimer disease

(2011) C. M. Roe et al.   NEUROLOGY

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease

(2010) Erik Portelius et al.   ACTA NEUROPATHOLOGICA

A New Hypothesis of Pathogenesis Based on the Divorce between Mitochondria and their Host Cells: Possible Relevance for Alzheimers Disease

(2010) L.F. Agnati et al.   Current Alzheimer Research

High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

(2010) Hiroaki Fukumoto et al.   FASEB JOURNAL

Neurotrophic factors in Alzheimer’s disease: role of axonal transport

(2010) K. Schindowski et al.   GENES BRAIN AND BEHAVIOR

The new Alzheimer’s criteria in a naturalistic series of patients with mild cognitive impairment

(2010) S. Galluzzi et al.   JOURNAL OF NEUROLOGY

Revising the definition of Alzheimer's disease: a new lexicon

(2010) Bruno Dubois et al.   LANCET NEUROLOGY

Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

(2010) Erik Portelius et al.   Molecular Neurodegeneration

Can Alzheimer disease be prevented by amyloid-β immunotherapy?

(2010) Cynthia A. Lemere et al.   Nature Reviews Neurology

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Cognitive effects of cell-derived and synthetically derived Aβ oligomers

(2010) Miranda N. Reed et al.   NEUROBIOLOGY OF AGING

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

Aβ40 Oligomers Identified as a Potential Biomarker for the Diagnosis of Alzheimer's Disease

(2010) Carol Man Gao et al.   PLoS One

Optimization protocol for amyloid-β peptides detection in human cerebrospinal fluid using SELDI TOF MS

(2010) Valentina Albertini et al.   Proteomics Clinical Applications

Markers of Alzheimer's disease in a population attending a memory clinic

(2009) Giovanni B. Frisoni et al.   Alzheimers & Dementia

Senescence, apoptosis, and stem cell biology: the rationale for an expanded view of intracrine action

(2009) Richard N. Re et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Decreased cerebrospinal fluid Aβ42correlates with brain atrophy in cognitively normal elderly

(2009) Anne M. Fagan et al.   ANNALS OF NEUROLOGY

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Hen or Egg?

(2009) Amin Rustom   Annals of the New York Academy of Sciences

A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease

(2009) Weiming Xia et al.   ARCHIVES OF NEUROLOGY

Detection of Amyloid-β Aggregates in Body Fluids: A Suitable Method for Early Diagnosis of Alzheimers Disease?

(2009) S. Funke et al.   Current Alzheimer Research

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Biomarkers for Alzheimer’s disease and other forms of dementia: Clinical needs, limitations and future aspects

(2009) Angel Cedazo-Minguez et al.   EXPERIMENTAL GERONTOLOGY

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

(2009) Niklas Mattsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Direct in Vivo Intracellular Selection of Conformation-sensitive Antibody Domains Targeting Alzheimer's Amyloid-β Oligomers

(2009) Giovanni Meli et al.   JOURNAL OF MOLECULAR BIOLOGY

Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study

(2009) Pieter Jelle Visser et al.   LANCET NEUROLOGY

Amyloid beta mediates memory formation

(2009) A. Garcia-Osta et al.   LEARNING & MEMORY

A novel pathway for amyloid precursor protein processing

(2009) Erik Portelius et al.   NEUROBIOLOGY OF AGING

Cystatin C is released in association with exosomes: A new tool of neuronal communication which is unbalanced in Alzheimer's disease

(2009) Roberta Ghidoni et al.   NEUROBIOLOGY OF AGING

Effects of γ-Secretase Inhibition on the Amyloid β Isoform Pattern in a Mouse Model of Alzheimer’s Disease

(2009) Erik Portelius et al.   Neurodegenerative Diseases

Oligomerization Partially Explains the Lowering of Aβ42 in Alzheimer’s Disease Cerebrospinal Fluid

(2009) Hillevi Englund et al.   Neurodegenerative Diseases

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

η-Secretase: Reduction of Amyloid Precursor Protein η-Site Cleavage in Alzheimers Disease

(2008) Fuyuki Kametani   Current Alzheimer Research

Amyloid-Related Biomarkers for Alzheimers Disease

(2008) Niels Andreasen et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

(2008) Robyn A. Sharples et al.   FASEB JOURNAL

Common key-signals in learning and neurodegeneration: focus on excito-amino acids, β-amyloid peptides and α-synuclein

(2008) L. F. Agnati et al.   JOURNAL OF NEURAL TRANSMISSION

Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation

(2008) Kohei Yuyama et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid   Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization

(2008) I. Klyubin et al.   JOURNAL OF NEUROSCIENCE

Exosomes: The Trojan horses of neurodegeneration

(2008) Roberta Ghidoni et al.   MEDICAL HYPOTHESES

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Itinerant exosomes: emerging roles in cell and tissue polarity

(2008) Aparna Lakkaraju et al.   TRENDS IN CELL BIOLOGY