Cytokines and Their Roles in the Pathogenesis of Systemic Lupus Erythematosus: From Basics to Recent Advances

Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN- 

(2014) M. B. Uccellini et al.   JOURNAL OF IMMUNOLOGY

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Potent Induction of IFN-  and Chemokines by Autoantibodies in the Cerebrospinal Fluid of Patients with Neuropsychiatric Lupus

(2014) D. M. Santer et al.   JOURNAL OF IMMUNOLOGY

Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus–prone B6.Sle1.Yaaanimals

(2009) Kenichiro Maeda et al.   BLOOD

Interleukin-17 and systemic lupus erythematosus: current concepts

(2009) A. Nalbandian et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Accuracy of cerebrospinal fluid IL-6 testing for diagnosis of lupus psychosis. A multicenter retrospective study

(2009) Shunsei Hirohata et al.   CLINICAL RHEUMATOLOGY

IL-6 Modulates CD5 Expression in B Cells from Patients with Lupus by Regulating DNA Methylation

(2009) S. Garaud et al.   JOURNAL OF IMMUNOLOGY

The Role of IL-23/IL-17 Axis in Lupus Nephritis

(2009) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

Interleukin 6 (IL-6) Deficiency Delays Lupus Nephritis in MRL-Faslpr Mice: The IL-6 Pathway as a New Therapeutic Target in Treatment of Autoimmune Kidney Disease in Systemic Lupus Erythematosus

(2009) H. CASH et al.   JOURNAL OF RHEUMATOLOGY

Raised expression of cytokine receptor gp130 subunit on peripheral lymphocytes of patients with active lupus. A useful tool for monitoring the disease activity?

(2009) M De La Torre et al.   LUPUS

Interleukin-6 release from peripheral mononuclear cells is associated to disease activity and treatment response in patients with lupus nephritis

(2009) Pasquale Esposito et al.   LUPUS

Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling

(2009) P. Pflegerl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age‐ and sex‐related patterns of serum interferon‐α activity in lupus families

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity

(2008) Chun Kwok Wong et al.   CLINICAL IMMUNOLOGY

IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice

(2008) Colin Edgerton et al.   CLINICAL IMMUNOLOGY

Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history

(2008) P FITZGERALDBOCARSLY et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Systemic IFN‐α drives kidney nephritis in B6.Sle123mice

(2008) Anna‐Marie Fairhurst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

(2008) S. Sigurdsson et al.   HUMAN MOLECULAR GENETICS

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

B cells flying solo

(2008) Joanna Groom et al.   IMMUNOLOGY AND CELL BIOLOGY

Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus

(2008) Richard Furie et al.   ARTHRITIS RESEARCH & THERAPY

Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients

(2008) Qiong Fu et al.   ARTHRITIS RESEARCH & THERAPY