Article
Infectious Diseases
Jaiberth Antonio Cardona-Arias, Luis Felipe Higuita-Gutierrez
Summary: The objective of this research was to analyze the impact of the COVID-19 pandemic on the seroprevalence of HIV, HBV, HCV, and HTLV I-II in blood donors. The study found that COVID-19 led to a decrease in donations from male, altruistic, and repetitive donors, as well as an increase in the age of donors. HIV prevalence increased, while HBV, HCV, and HTLV I-II prevalence decreased. These findings highlight the importance of improving epidemiological surveillance and investigating these infections.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Review
Virology
Tania H. Mulherkar, Daniel Joseph Gomez, Grace Sandel, Pooja Jain
Summary: Dendritic cells play a crucial role in the infections of HIV-1 and HTLV-1 and are associated with neurodegenerative diseases and cancer. Infected dendritic cells can transmit the infection to other cells and contribute to the development of neurodegenerative diseases. Current vaccines and therapies targeting host-pathogen interactions can be applied to patients with these diseases.
Review
Medicine, General & Internal
Alberta Lucchese, Dario Di Stasio, Antonio Romano, Fausto Fiori, Guido Paolo De Felice, Carlo Lajolo, Rosario Serpico, Francesco Cecchetti, Massimo Petruzzi
Summary: This review evaluated the correlation between viral infections (HPV, EBV, HSV-1, CMV) other than HCV and oral lichen planus. The results showed inconclusive evidence regarding the involvement of these viruses in the etiopathogenesis of the disease. Further studies are needed to enhance the translation of research into clinical practice.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Serena Zaltron, Anna Cambianica, Marco Di Gregorio, Cosimo Colangelo, Samuele Storti, Giorgio Tiecco, Francesco Castelli, Eugenia Quiros-Roldan
Summary: We report a case of occult hepatitis B virus infection (OBI) reactivation in a HIV/HCV co-infected patient who was followed for 25 years but lost to follow-up after Direct-acting antivirals (DAAs) treatment. The patient showed severe immunosuppression and high replication of plasmatic HIV-RNA, followed by an immune reconstitution inflammatory syndrome (IRIS) with detectable HBV-DNA load and transaminase elevation after ART reintroduction. This case highlights the importance of closely monitoring HBV serological and virological markers in individuals with impaired immune systems, especially in patients on tenofovir or lamivudine-sparing regimens.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Infectious Diseases
Salima Davlidova, Zoe Haley-Johnson, Kate Nyhan, Ayesha Farooq, Sten H. Vermund, Syed Ali
Summary: In Central Asia and the Caucasus, the prevalence of HIV, HCV, and HBV remains exceedingly high among selected populations, notably among people who inject drugs (PWID) and men who have sex with men (MSM).
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Virology
Estela Luz, Marinho Marques, Eduardo Martins Netto, Luisa Meireles Campos, Savio Amaral, Iraildes Santana, Eduardo Luz Marques, Carlos Brites
Summary: Through evaluating the results of serological and NAT tests in blood donors, the study found that HBV infection rate predominated, with a decreasing trend in DTI rates, and NAT played an important role in improving transfusion safety.
Article
Mathematics, Applied
A. M. Elaiw, N. H. AlShamrani
Summary: This paper formulates a within-host dynamics model for HIV/HTLV-I co-infection, taking into account different transmission pathways and time delays. The theoretical results are validated through numerical simulations and stability analysis, and the impact of HTLV-I infection on HIV dynamics is discussed.
MATHEMATICAL METHODS IN THE APPLIED SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Tullio Prestileoa, Vito Di Marco, Ornella Dino, Adriana Sanfilippo, Marco Tutone, Maurizio Milesi, Lorenza Di Marco, Camila A. Picchio, Antonio Craxi, Jeffrey V. Lazarus
Summary: This study demonstrates the effectiveness and feasibility of infectious disease screening programs for migrants. The results show that migrants from Africa are vulnerable to infection with hepatitis B virus, hepatitis C virus, and human immunodeficiency virus during their journey. Women, individuals who stayed in Libya for a long time, and those who experienced physical and/or sexual violence are more susceptible to viral infections.
DIGESTIVE AND LIVER DISEASE
(2022)
Article
Virology
Adele Caterino-de-Araujo, Karoline R. Campos, Luanda M. S. Oliveira, Paula O. Rigato
Summary: HIV, HTLV-1/-2, and HCV share routes of transmission, and co-infection can lead to worse outcomes. This study analyzed biomarkers in HIV-infected individuals and found differences in cytokines/chemokines, T cells, and viral load among different groups. Although the sample size is small and the study design is cross-sectional, the findings suggest a negative impact of HTLV-1 and a possible protective role of HTLV-2 in HIV infection progression.
Review
Biochemistry & Molecular Biology
Malthe Fredsgaard, Samba Evelyne Kabemba Kaniki, Io Antonopoulou, Tanmay Chaturvedi, Mette Hedegaard Thomsen
Summary: Despite global efforts to mitigate public health risks, viral outbreaks continue to remind us of our vulnerability to biological hazards. The Salicornia genus, known for its saltwater-tolerant plants, shows potential in producing clinically applicable phytochemicals that exhibit antiviral activities. This review focuses on the antiviral effects of phenolic compounds found in Salicornia spp., suggesting their potential use as therapeutic medicine against influenza A, hepatitis B and C, and HIV-1. These findings may contribute to the development of new antiviral nutraceuticals and pharmaceuticals to combat viral pandemics, ultimately improving public health.
Article
Virology
Christoph Niederhauser, Caroline Tinguely, Martin Stolz, Michael Vock, Soraya Amar El Dusouqui, Peter Gowland
Summary: Switzerland has significantly reduced the prevalence, incidence, and residual risk of blood-borne infections over the past 25 years through strict donor selection criteria, improved questionnaires, sensitive serological screening tests, and the implementation of nucleic acid testing.
Article
Oncology
Myriam Taouqi, Marianne Veyri, Sylvie Bregigeon, Michele Pibarot, Caroline Solas, Alain Makinson, Anne-Genevieve Marcelin, Sylvain Choquet, Jean-Philippe Spano, Isabelle Poizot-Martin
Summary: The study assessed screening practices in cancer patients and professional satisfaction with the CancerHIV network, revealing low rates of HIV, HBV, and HCV screening at the initial cancer assessment stage. However, satisfaction with regional or national treatment options was high among respondents.
BULLETIN DU CANCER
(2021)
Article
Multidisciplinary Sciences
Jie Yang, Jin-Long Lin, Jing Liu, Xiao-Wen Jiang, Hao Zhang, Lei Peng
Summary: This study examined the prevalence and trends of smoking among people living with HIV, HBV, or HCV, and found that infected individuals had a higher smoking rate and lower smoking cessation rate. Age, gender, education level, economic level, employment status, depression, and drug use were identified as factors related to smoking behavior among these infected people.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Milagros Munoz-Chimeno, Jorge Valencia, Alvaro Rodriguez-Recio, Guillermo Cuevas, Alejandra Garcia-Lugo, Samuel Manzano, Vanessa Rodriguez-Paredes, Beatriz Fernandez, Lucia Morago, Concepcion Casado, Ana Avellon, Pablo Ryan
Summary: This study compared the performance of point of care rapid diagnostic tests (POC-RDT) with laboratory conventional tests in viral infection screening. The POC-RDT method was found to provide immediate results and facilitate diagnosis, making it suitable for screening high-risk populations.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Jie Yang, Hao Zhang, Jin-Long Lin, Jing Liu, Xiao-Wen Jiang, Lei Peng
Summary: This study investigated the association between serum VOCs and cotinine in smokers infected with HIV, HBV, or HCV. The results showed that the intensity of the association between VOCs and cotinine was the strongest in smokers with the largest exposure dose to tobacco. High concentrations of 1,2-Dichlorobenzene, Benzene, Carbon Tetrachloride, and 2,5-Dimethylfuran in blood might be independent risk factors leading to the increase of serum metabolite cotinine in smokers.
SCIENTIFIC REPORTS
(2022)