Article
Multidisciplinary Sciences
Alex Dikopoltsev, Yonatan Sharabi, Mark Lyubarov, Yaakov Lumer, Shai Tsesses, Eran Lustig, Ido Kaminer, Mordechai Segev
Summary: Photonic time-crystals are spatially homogeneous media that exhibit periodic variations in their electromagnetic susceptibility, leading to temporal reflections and refractions of propagating waves. Free electrons in these crystals spontaneously emit radiation, with a significantly amplified emission process when associated with momentum-gap modes. Quantum interference between spontaneous emission and electron emission into the band modes suppresses the interdependent emission. Therefore, the study of free-electron physics in photonic time-crystals offers a platform to explore various exciting phenomena.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Editorial Material
Multidisciplinary Sciences
Nicholas Rivera
Summary: Shining a laser on an iron wire generates fast-moving electrons that amplify electromagnetic waves created by the light interacting with the wire. This method of generating laser-like light could be more effective than existing electron-based methods.
Editorial Material
Multidisciplinary Sciences
Eric O. Potma
Summary: Molecular vibrational signals, which are difficult to detect, can be revealed in bioimaging techniques using light in a 'squeezed' quantum state.
Editorial Material
Multidisciplinary Sciences
Hector Lopez-Rios, Monica Olvera de la Cruz
Summary: A study has demonstrated that light-sensitive particles can stratify in a solution, altering the color of the entire suspension. This system creates a color-changing ink that has the potential to make electronic paper a viable technology.
Editorial Material
Multidisciplinary Sciences
Huaqiang Wu, Qionghai Dai
Summary: The explosive growth of artificial intelligence is driving the need for increased computing power, which could be met by two reported photonic processors that have the potential to revolutionize AI hardware.
Review
Nanoscience & Nanotechnology
Daniel Midtvedt, Vasilii Mylnikov, Alexander Stilgoe, Mikael Kall, Halina Rubinsztein-Dunlop, Giovanni Volpe
Summary: The deep-learning revolution is providing new opportunities for manipulating and harnessing light. It has already shown success in improving the design of nanophotonic devices and analyzing experimental data. However, challenges arise in understanding and interpreting the results and reliability of deep learning.
Correction
Biochemical Research Methods
Janet A. H. Tang, Charles E. Granger, Karteek Kunala, Keith Parkins, Khang T. Huynh, Kristen Bowles-Johnson, Qiang Yang, Jennifer J. Hunter
Summary: This erratum corrects an error in Table 4 of our paper [Biomed. Opt. Express 13, 1737 (2022)].
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Optics
Francisco J. Diaz-Fernandez, Javier Marti, Carlos Garcia-Meca
Summary: Invisibility cloaks are a significant development in the field of metamaterials. While most efforts have been focused on improving the effectiveness of cloaks, little attention has been paid to the development of efficient techniques for detecting invisibility devices. This study proposes a different approach using diffraction tomography to enhance efficiency in detecting and obtaining images of invisibility cloaks, leading to improved sensitivity and potential application in sound cloaks.
LASER & PHOTONICS REVIEWS
(2023)
Article
Optics
Khadijeh Miarabbas Kiani, Henry C. Frankis, Cameron M. Naraine, Dawson B. Bonneville, Andrew P. Knights, Jonathan D. B. Bradley
Summary: This research presents a new method for achieving optical gain and lasing on a silicon photonics platform, which allows for low-cost, high-volume manufacturing and co-integration with silicon devices.
LASER & PHOTONICS REVIEWS
(2022)
Article
Materials Science, Multidisciplinary
I. Tiliouine, G. Granger, C. E. Jimenez-Durango, Y. Leventoux, B. Wetzel, V. Couderc, S. Fevrier
Summary: We demonstrate the generation of a two-octave mid-infrared supercontinuum in unprocessed large core chalcogenide fiber, using a fiber-based laser that delivers 35 kW, 180 fs pulses at 4.53 μm.
RESULTS IN PHYSICS
(2023)
Article
Optics
C. Cuadrado-Laborde, J. L. Cruz, A. Diez, M. V. Andres
Summary: We discuss a method to determine the group delay and phase of a given pulse in the Fourier optics domain. The proposal involves measuring two intensity spectra before and after a known quadratic phase modulation. An analytical equation is then used to determine the group delay in one step, with the option to determine the spectral phase through spectral integration if needed. The proposal is supported by numerical results and experimental measurement.
OPTICS COMMUNICATIONS
(2022)
Review
Physics, Multidisciplinary
Taira Giordani, Walter Schirmacher, Giancarlo Ruocco, Marco Leonetti
Summary: Anderson localization is an interference effect that drastically reduces the diffusion of wave packets in the presence of strong disorder. This effect has been observed in dimensionally reduced systems, particularly in optical fibers exhibiting transverse localization. Advances in fabrication technology and experimental techniques have brought localization closer to applications such as quantum communication and image transport.
FRONTIERS IN PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Siqi Yan, Jeremy Adcock, Yunhong Ding
Summary: This review focuses on the application of graphene in high-performance silicon photonic devices and discusses the future trends and challenges of silicon-graphene hybrid photonic devices.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Multidisciplinary
Ho Jin Jang, Jun Yeob Lee
Summary: The device lifetime of exciplex organic light-emitting diodes was extended by almost four times through control of the p-type material content by mimicking the host-dopant system. The major pathway to stabilize the exciplex devices was suppression of triplet exciton loss by strong intermolecular interaction and concentration quenching. dispersing p-type material in the bipolar n-type material was effective to elongate the device lifetime of the exciplex based organic light-emitting diodes.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Engineering, Environmental
Adrian Monteleone, Folker Wenzel, Heinz Langhals, Daniel Dietrich
Summary: The FLIM method was tested for identification and characterization of six types of plastics, showing significant differentiation in 94.55% of the comparisons. Results suggest that FLIM has the potential for sub-micrometer plastic characterization and allows for visual 3D-sectioning of samples, which could be important for identifying and characterizing plastics in tissue and environmental samples.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Geriatrics & Gerontology
Jared M. Campbell, Saabah Mahbub, Abbas Habibalahi, Sharon Paton, Stan Gronthos, Ewa Goldys
Summary: The study used non-destructive multispectral assessment to investigate the metabolic mechanisms of in vitro mesenchymal stem cell (MSC) ageing. By analyzing spectral signals for different fluorophores in MSCs over serial passages, the researchers were able to develop a reliable model for categorizing the age of culture-expanded MSCs accurately.
Review
Biochemical Research Methods
Shalini Aggarwal, Arup Acharjee, Amrita Mukherjee, Mark S. Baker, Sanjeeva Srivastava
Summary: This article critically analyzes the pathobiology of SARS-CoV-2 in humans using high-throughput omics technologies, revealing changes in biological pathways associated with COVID-19 disease. Further meta-analysis indicates significant alterations in immune response, fatty acid, and amino acid metabolism in COVID-19 patients.
JOURNAL OF PROTEOME RESEARCH
(2021)
Article
Biochemical Research Methods
Seong Beom Ahn, Karthik S. Kamath, Abidali Mohamedali, Zainab Noor, Jemma X. Wu, Dana Pascovici, Subash Adhikari, Harish R. Cheruku, Gilles J. Guillemin, Matthew J. McKay, Edouard C. Nice, Mark S. Baker
Summary: The study successfully identified cancer-associated low abundance plasma proteins using a mixture of selected recombinant proteins and SWATH/DIA identification method, addressing the challenge of detecting low abundance proteins in precision medicine biomarker discovery with mass spectrometry.
JOURNAL OF PROTEOME RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Sandhya Clement, Anna Guller, Saabah B. Mahbub, Ewa M. Goldys
Summary: Radiodynamic therapy (RDT) is a promising non-invasive anti-cancer treatment that generates reactive oxygen species (ROS) through X-ray and a photosensitizer drug. A novel nanoparticle drug formulation for RDT, consisting of poly (lactic-co-glycolic acid) (PLGA) nanoparticles co-loaded with a photosensitizer drug verteporfin (VP) and an oxygen-carrying molecule, perfluorooctylbromide (PFOB), showed significant increase in ROS production under both normoxic and hypoxic conditions. RDT with these nanoparticles effectively killed pancreatic cancer cells and suppressed tumor cell outgrowth, demonstrating potential for treating deep-seated hypoxic tumors.
Article
Obstetrics & Gynecology
Tiffany C. Y. Tan, Saabah B. Mahbub, Jared M. Campbell, Abbas Habibalahi, Carl A. Campugan, Ryan D. Rose, Darren J. X. Chow, Sanam Mustafa, Ewa M. Goldys, Kylie R. Dunning
Summary: The study successfully differentiated between euploid and aneuploid ICM cells in mouse blastocysts using hyperspectral autofluorescence microscopy. Further validation in human embryos is needed to confirm the approach's effectiveness.
HUMAN REPRODUCTION
(2022)
Article
Biochemistry & Molecular Biology
Anna Guller, Inga Kuschnerus, Vlada Rozova, Annemarie Nadort, Yin Yao, Zahra Khabir, Alfonso Garcia-Bennett, Liuen (Olivia) Liang, Aleksandra Polikarpova, Yi Qian, Ewa M. Goldys, Andrei V. Zvyagin
Summary: The study established an in vitro/in vivo model to investigate organ-specific micrometastases of triple-negative breast cancer using a chick embryo experimental platform. The model demonstrated potential applications in cancer research, drug development, and nanomedicine, providing insights into the colonization process of TNBC cells in distant organs.
Article
Geriatrics & Gerontology
Jared M. Campbell, Saabah B. Mahbub, Michael J. Bertoldo, Abbas Habibalahi, Dale M. Goss, William L. Ledger, Robert B. Gilchrist, Lindsay E. Wu, Ewa M. Goldys
Summary: Increasing age has a negative impact on female fertility due to deteriorating quality of oocytes. The use of nicotinamide mononucleotide (NMN) has been shown to restore oocyte quality and fertility in aged animals. Identifying the multispectral profile of oocyte autofluorescence during aging could serve as a non-invasive and sensitive measure of oocyte quality.
Article
Oncology
Abbas Habibalahi, Alexandra Allende, Jesse Michael, Ayad G. Anwer, Jared Campbell, Saabah B. Mahbub, Chandra Bala, Minas T. Coroneo, Ewa M. Goldys
Summary: This study introduces an imaging-based method for screening ocular surface squamous neoplasia, which will reduce pressure on health resources and potentially eliminate the need for eye biopsy in suspected cases.
Article
Biochemistry & Molecular Biology
Sarah Teakel, Michealla Marama, David Aragao, Sofiya Tsimbalyuk, Emily R. R. Mackie, Tatiana P. Soares da Costa, Jade K. Forwood, Michael A. Cahill
Summary: This study reports that the membrane-associated progesterone receptor protein family originated from a new class of prokaryotic cytochrome b(5) domain proteins. It also suggests that the heme orientation of MAPR-like proteins was inherited from the prokaryotic ancestor.
Article
Biochemistry & Molecular Biology
Bashar M. Thejer, Vittoria Infantino, Anna Santarsiero, Ilaria Pappalardo, Francesca S. Abatematteo, Sarah Teakel, Ashleigh Van Oosterum, Robert H. Mach, Nunzio Denora, Byung Chul Lee, Nicoletta Resta, Rosanna Bagnulo, Mauro Niso, Marialessandra Contino, Bianca Montsch, Petra Heffeter, Carmen Abate, Michael A. Cahill
Summary: Sigma-2 receptor (S2R) is functionally associated with both transmembrane protein TMEM97 and translocator protein (TSPO). This study provides evidence of the interaction between S2R and TSPO, as well as the physical colocalization of TMEM97 and TSPO in certain cancer cells. Additionally, the role of S2R-interacting partner PGRMC1 was clarified. This is the first suggestion of a functional interaction between TSPO and TMEM97, which can be influenced by S2R ligands.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biotechnology & Applied Microbiology
Nitin Chitranshi, Rashi Rajput, Angela Godinez, Kanishka Pushpitha, Mehdi Mirzaei, Devaraj Basavarajappa, Veer Gupta, Samridhi Sharma, Yuyi You, Giovanna Galliciotti, Ghasem H. Salekdeh, Mark S. Baker, Stuart L. Graham, Vivek K. Gupta
Summary: Our research shows that oxidation deactivation impairs the inhibitory activity of the serine protease inhibitor neuroserpin (NS) in glaucoma. The loss of NS is detrimental to retinal structure and function, and perturbations in autophagy and microglial and synaptic markers are associated with NS ablation. On the other hand, upregulation of NS promotes retinal ganglion cell (RGC) survival and protects against glaucoma-induced degeneration.
Review
Biochemistry & Molecular Biology
Michael A. Cahill
Summary: This paper discusses the role of ancient protein PGRMC in modern human health and diseases, and proposes its key functions in neurogenesis and nerve-gut communication, as well as its possible involvement in circadian nicotinamide adenine dinucleotide synthesis. The paper also suggests that Alzheimer's disease most closely reflects the suite of functions related to PGRMC biology.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2022)
Review
Biochemistry & Molecular Biology
Michael A. Cahill
Summary: This paper discusses the evolutionary functional changes of PGRMC proteins, suggesting that key functions originated in early eukaryotes and further developed in the last eumetazoan common ancestor. Modern PGRMC proteins play important roles in regulating various biological functions.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2022)
Article
Nanoscience & Nanotechnology
Kaiser N. Madlum, Entidhar Jasim Khamees, Shaymaa Ahmed Abdulridha, Reem Akram Naji
Summary: An ablative pulsed laser is an efficient physical technique for synthesizing highly purified nanoparticles in liquid environments. This study successfully synthesized biologically active platinum nanoparticles with high antimicrobial activity against Pseudomonas and cytotoxic effects on cancer cell lines.
JOURNAL OF NANOSTRUCTURES
(2021)
Review
Biochemical Research Methods
Zainab Noor, Seong Beom Ahn, Mark S. Baker, Shoba Ranganathan, Abidali Mohamedali
Summary: Accurate protein identification is crucial in proteomics, with mass spectrometry being the primary technique used. Understanding data generation and parameters used in computational tools is essential for proper protein identification. Bioinformatics and computational methodologies are also important for validating protein identification in proteomics.
BRIEFINGS IN BIOINFORMATICS
(2021)