Article
Cardiac & Cardiovascular Systems
Mie Kunio, Joseph A. Gardecki, Kohei Watanabe, Kensuke Nishimiya, Sarika Verma, Farouc A. Jaffer, Guillermo J. Tearney
Summary: This study investigates the histopathological origins of near infrared auto-fluorescence (NIRAF) in human cadaver coronary arteries. The results show that NIRAF is associated with high-risk morphological features and can provide additional information for identifying high-risk coronary plaques.
Article
Chemistry, Multidisciplinary
Qiaozhi Yu, Zhengjian Yao, Haolin Zhang, Zhibin Li, Zhixing Chen, Hanqing Xiong
Summary: Researchers have developed a new ultrafast time-domain spectroscopy technique called transient stimulated Raman excited fluorescence (T-SREF), which enables background-free Raman spectra of electronic-coupled vibrational modes. By exciting the sample with two successive broadband femtosecond pulse pairs and performing Fourier transform on the resulting time-domain fluorescence trace, T-SREF achieves high sensitivity at the level of a few molecules, paving the way for supermultiplexed fluorescence detection and molecular dynamics sensing.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Edward Curran Eggertson, Francesca Venturini
Summary: This study investigates the changes in carotenoid concentration in extra virgin olive oil (EVOO) as it oxidizes under accelerated thermal aging using resonant Raman spectroscopy (RRS). The conventional method, HPLC, used to determine carotenoid concentration is costly and time-consuming. The study finds that the resonant Raman technique amplifies the weak carotenoid signals and identifies Raman intensity ratios as indicators of aging effects.
Article
Hematology
Mazen S. Albaghdadi, Ryutaro Ikegami, Mohamad B. Kassab, Joseph A. Gardecki, Mie Kunio, Mohammed M. Chowdhury, Ramzi Khamis, Peter Libby, Guillermo J. Tearney, Farouc A. Jaffer
Summary: The study shows that NIRAF is associated with lipid and oxidative stress, generated through oxidized lipid-driven oxidative stress, and supports ceroid as a source of NIRAF in human atherosclerosis.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Article
Optics
Lara Sophie Theurer, Bernd Sumpf, Martin Maiwald, Andre Mueller, Joerg Fricke, Peter Ressel, Andrea Knigge, Guenther Traenkle
Summary: An experimental comparison was conducted between individual and common wavelength-operation modes of a Y-branch distributed Bragg reflector (DBR) ridge waveguide laser at 785 nm, which had an electrically adjustable spectral distance. The Y-branch laser combined two laser cavities via a Y-section to a common output section. Different DBR gratings were used in the two cavities to set the emission wavelengths of the two branches. Separate wavelength tuning of the two branches was achieved by resistive heater elements, allowing for alternating emission wavelengths for applications such as differential absorption spectroscopy or shifted excitation Raman difference spectroscopy. The common wavelength operation also generated two emission lines suitable for generating THz radiation using difference frequency mixing. The devices could potentially be used as single-chip light sources for a combination of Raman and THz applications. In the wavelength-operation comparison, the devices achieved optical output powers of about 105 and 185 mW in individual and common wavelength-operation modes, respectively. The devices showed spectral single-mode emission over the whole operation range in individual operation mode, and predominantly single-mode spectral emission up to an optical output power of 65 mW in common operation mode. Flexible frequency difference between 0 and 0.8 THz (0 and 1.6 nm) with predominantly single-mode spectral emission was obtained in both wavelength operation modes.
Article
Chemistry, Physical
Sunny Tiwari, Adarsh B. Vasista, Diptabrata Paul, Shailendra K. Chaubey, G. V. Pavan Kumar
Summary: Experimental observation of beaming elastic and surface enhanced Raman scattering (SERS) emission from a bent-nanowire on a mirror (B-NWoM) cavity. The system utilized a self-assembled monolayer of molecules with a well-defined molecular orientation to achieve beaming SERS emission.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Applied
Shengnan Wang, Danni Qu, Guilan Zhao, Lina Yang, Lijie Zhu, Hong Song, He Liu
Summary: The microstructure and properties of the soy hull polysaccharide interfacial layer are significantly affected by pH, with higher stability at high pH levels but increased structural order at low pH levels. Low pH reduces thermal stability and increases viscosity of the emulsion, while high pH leads to higher viscosity.
Article
Spectroscopy
Hongpeng Wang, Yingjian Xin, Xiong Wan
Summary: This paper reports on the spectral characterization of porphyrins and terpenoids in different vegetable oils, classifying them using a PCA-SVM model. The study analyzed the effects of oil types and processing technology on spectral differences, finding that chlorophyll and β-carotene were the main contributors to the fingerprint information in the spectral techniques. Extra virgin olive oil obtained by physical cold pressing had the highest content of porphyrins and terpenoids, indicating the strongest activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Food Science & Technology
Monica Mburu, Clement Komu, Olivier Paquet-Durand, Bernd Hitzmann, Viktoria Zettel
Summary: The study successfully detected the amount of adulterated oils using spectroscopic analysis, with a classification accuracy of 90% for identifying adulterated chia oils. The classification methods showed good results, with SVM being the most effective in identifying the adulteration oil.
Article
Chemistry, Multidisciplinary
Stefan Krause, Evelyn Ploetz, Johann Bohlen, Patrick Schuler, Renukka Yaadav, Florian Selbach, Florian Steiner, Izabela Kaminska, Philip Tinnefeld
Summary: Researchers screened 10 preparation methods for graphene-on-glass and presented an optimized protocol for single-molecule and super-resolution imaging; they utilized DNA origami technology to detect graphene quality, showing discrepancies between conventional techniques such as light microscopy, atomic force microscopy, and Raman spectroscopy for graphene characterization.
Article
Biophysics
Shayan Valijam, Daniel P. G. Nilsson, Rasmus Oberg, Unni Lise, Albertsdottir Jonsmoen, Adrian Porch, Magnus Andersson, Dmitry Malyshev
Summary: In this study, a microfluidic lab-on-chip based on CPW was used to disrupt bacterial spores and release their biomarkers. Fluroescence spectroscopy and laser tweezers Raman spectroscopy were employed to detect the disruption of spores and the loss of calcium dipicolinic acid. Scanning electron microscopy also confirmed the visible disruption of spores after microwave exposure. This study demonstrates the advantages of using CPW for spore disruption and biomarker detection.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Biochemistry & Molecular Biology
Anni Kumari, Kristian K. Kristensen, Michael Ploug, Anne-Marie Lund Winther
Summary: LPL plays a crucial role in lipid metabolism by hydrolyzing triglyceride-rich lipoproteins, and its impaired activity can lead to hypertriglyceridemia. In addition to LDL-C, hypertriglyceridemia is also an independent risk factor for atherosclerosis, with LPL and other factors involved in intravascular lipolysis playing a key role in this process.
Article
Materials Science, Ceramics
Umang Berwal, Vinod Singh, Rinku Sharma
Summary: This study investigates the optical and structural properties of pyrochlore oxide Gd2-xTbxTi2O7, and finds that the doping of rare-earth element leads to structural distortion and the production of defects. With increasing doping concentration, the particle size and spectral characteristics of the compounds change accordingly.
CERAMICS INTERNATIONAL
(2022)
Article
Food Science & Technology
Yaotong Liu, Mingmin Qing, Jingnan Zang, Yujie Chi, Yuan Chi
Summary: Salted egg yolks are highly regarded by consumers for their taste and processing characteristics. This study compared the effects of CaCl2 on the salting process of egg yolks and found that CaCl2 increased the mass transfer and diffusion coefficient, resulting in changes in the texture, water migration, protein aggregation, and structure of salted egg yolks. The addition of CaCl2 promoted the precipitation of lipids, dehydration of egg yolk, and bulk aggregation of proteins. The analysis of protein structures showed changes in the content of beta-sheets, irregular curls, alpha-helices, and beta-turns. Overall, the addition of CaCl2 improved the degree of protein polymerization and could be used to enhance the quality of salted egg yolks.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Clinical Neurology
Pierre C. Amarenco, Philippa S. Lavallee, Jong Kim, Julien Labreuche, Hugo Charles, Maurice Giroud, Byung-Chul Lee, Marie-Helene Mahagne, Elena Meseguer, Norbert Nighoghossian, Philippe Gabriel Steg, Eric Vicaut, Eric Bruckert, Treat Stroke Target Invest
Summary: This study investigated the effects of two different strategies for reducing low-density lipoprotein (LDL) cholesterol on reducing cardiovascular risk. The results showed that among patients with a target LDL cholesterol level of <70 mg/dL, a reduction in LDL cholesterol of >50% from baseline significantly reduced the risk of the primary outcome.
