Journal
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 7, Issue 1, Pages 56-56Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2011.1199
Keywords
Apoptosis of Lymphocytes; Gold-Curcumin; Nanoconjugate
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The use of nano-particles in several areas necessitates the understanding of their interaction with cells, tissues and experimental animals. In the present study, the effect of a curcumin conjugated gold nano-particle on peripheral blood lymphocytes was investigated. The treated lymphocytes revealed features typical of apoptosis which include chromatin condensation, and membrane blebbing and occurrence of apoptotic bodies. The observations indicate that these nanoparticle conjugates may find use as drugs in non-toxic range observed in cytotoxicity studies.
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