Metallic wear debris may regulate CXCR4 expressionin vitroandin vivo

What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles?

(2016) Rocky S. Tuan et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target

(2013) Tzu-hua Lin et al.   Acta Biomaterialia

Periprosthetic Tissue Metal Content but Not Serum Metal Content Predicts the Type of Tissue Response in Failed Small-Diameter Metal-on-Metal Total Hip Arthroplasties

(2013) C.H Lohmann et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Metal-On-Metal Bearings, Inflammatory Pseudotumours and Their Neurological Manifestations

(2012) Bhupinder S. Mann et al.   Hip International

Adverse reactions to metal debris: histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties

(2012) Sonali Natu et al.   JOURNAL OF CLINICAL PATHOLOGY

Orthopedic wear debris mediated inflammatory osteolysis is mediated in part by NALP3 inflammasome activation

(2012) Lyndsey Burton et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Modern Metal-on-Metal Hip Implants

(2012) Kevin J. Bozic et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Metal-on-Metal Total Hip Arthroplasty: Causes and High Incidence of Early Failure

(2012) David Fabi et al.   ORTHOPEDICS

How safe are metal-on-metal hip implants?

(2012) D. Cohen   BMJ-British Medical Journal

New Insights into Wear and Biological Effects of Metal-on-Metal Bearings

(2011) Isabelle Catelas et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Metal-on-metal bearings

(2011) F. S. Haddad et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

LPS Promotes Pre-osteoclast Activity by Up-regulating CXCR4 via TLR-4

(2011) Q. Xing et al.   JOURNAL OF DENTAL RESEARCH

Failed Metal-on-Metal Hip Arthroplasties: A Spectrum of Clinical Presentations and Operative Findings

(2010) James A. Browne et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Metal-on-metal bearings total hip arthroplasty: The cobalt and chromium ions release concern

(2010) C. Delaunay et al.   Orthopaedics & Traumatology-Surgery & Research

Recent advances on the use of the CXCR4 antagonist plerixafor (AMD3100, Mozobil™) and potential of other CXCR4 antagonists as stem cell mobilizers

(2010) Erik De Clercq   PHARMACOLOGY & THERAPEUTICS

Over-expression of receptor activator of nuclear factor-κB ligand (RANKL), inflammatory cytokines, and chemokines in periprosthetic osteolysis of loosened total hip arthroplasty

(2009) Chen-Ti Wang et al.   BIOMATERIALS

Integrin and chemokine receptor gene expression in implant-adherent cells during early osseointegration

(2009) Omar Omar et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF- B pathways and promotes osteoclastogenesis in human oral cancer cells

(2008) C.-H. Tang et al.   CARCINOGENESIS