Article
Dentistry, Oral Surgery & Medicine
Noha Morsy, Mohammed El Kateb, Amir Azer, Said Fathalla
Summary: The study aimed to compare the accuracy of conventional and digital impressions for producing three-unit FPDs. Results showed that digital impressions resulted in better marginal and internal fit for the FPDs, while the trueness and precision of both conventional and digital techniques were comparable.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Paula Pontevedra, Carlos Lopez-Suarez, Veronica Rodriguez, Jesus Pelaez, Maria J. Suarez
Summary: This study evaluated and compared the clinical performance and survival rate of posterior monolithic and veneered zirconia fixed partial dentures. The results suggest that monolithic zirconia and complete digital flow could be a viable alternative to veneered zirconia in the posterior regions.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Paula Pontevedra, Carlos Lopez-Suarez, Veronica Rodriguez, Celia Tobar, Jesus Pelaez, Maria Suarez
Summary: The study evaluated and compared the survival rates, success rates, and complications of three-unit posterior monolithic and veneered zirconia and metal-ceramic fixed partial dentures (FPDs) fabricated using a digital workflow and CAD/CAM over a 5-year follow-up. The results showed that veneered zirconia and metal-ceramic FPDs had higher 5-year survival rates, and the margin index remained stable in both zirconia groups. Digital workflow was found to be an adequate treatment option, and monolithic zirconia could be a viable alternative. However, further long-term studies are needed for patients with bruxism.
JOURNAL OF PROSTHODONTIC RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Paula Pontevedra, Carlos Lopez-Suarez, Jesus Pelaez, Sara Garcia-Serdio, Maria J. Suarez
Summary: The study evaluated the clinical performance and survival rate of posterior monolithic zirconia fixed partial dentures over a 2-year period. Results showed a high survival rate of 100% at 2 years, satisfactory quality of restorations, improvement in gingival and plaque index at the 2-year follow-up, and stable margin index throughout the follow-up period.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2021)
Article
Materials Science, Biomaterials
Kai Li, Shiwei Liu, Jieping Li, Deliang Yi, Dandan Shao, Tao Hu, Xuebin Zheng
Summary: Synthesizing Mn-doped nanowire-structured TiO2 coatings on Ti implants enhances osteoblastic responses and improves cell adhesion and bone formation activity through integrin-mediated pathways.
BIOMATERIALS SCIENCE
(2023)
Review
Dentistry, Oral Surgery & Medicine
Wanjin Kim, Xiao Chun Li, Avinash S. Bidra
Summary: The study shows that implant-supported monolithic zirconia crowns and fixed partial dentures have excellent short-term survival rates, but the evidence for medium-term and long-term survival rates is lacking.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
R. J. Wierichs, W. Weilenmann, S. Jeganathan, P. Perrin
Summary: This study analyzed the longevity of direct metal-wire reinforced composite fixed partial dentures (MRC-FPD) and the factors influencing their survival and success. The results showed that the number of metal wires, dentist's experience, patient's caries risk, and bruxism significantly affected the failure rate. The study suggests that MRC-FPD can be an immediate, short- and medium-term solution for replacing missing teeth.
Article
Dentistry, Oral Surgery & Medicine
Mazen A. Attia, Mohamed Radwan, Liam Blunt, Paul Bills, Ahmed Tawfik, Ahmed M. Arafa
Summary: This study aimed to test the effect of different sintering protocols on the fracture strength of 3-unit monolithic gradient zirconia fixed partial dentures (FPDs). The results showed that FPDs sintered using the high-speed sintering protocol had the highest fracture load and the smallest grain size, indicating the best mechanical properties.
JOURNAL OF PROSTHETIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Mohammed Abdullah Hawthan, Bruno R. Chrcanovic, Christel Larsson
Summary: This study aimed to assess the influence of several factors on the survival rate of tooth-supported fixed partial dentures (FPDs) with vital and non-vital abutments. A total of 331 FPDs in 229 patients were included in the study. It was found that smoking and the type of prosthesis material significantly influenced the survival of FPDs, while abutment vitality, position of the non-vital abutment, or prosthesis length did not show any significant influence on the occurrence of prosthesis failure.
JOURNAL OF PROSTHODONTIC RESEARCH
(2023)
Article
Chemistry, Physical
Janna Lowensohn, Laurie Stevens, Daniel Goldstein, Bortolo Matteo Mognetti
Summary: A quantitative model of ligand-presenting particles' mobility at the interface is crucial for understanding important systems in biology and nanotechnology. This study investigates the dynamics of particles featuring ligands selectively binding receptors decorating an interface, and shows that the formation of ligand-receptor complexes and reversible bridges affect the particles' average position. The study presents two analytic equations to quantify the sliding diffusion constant of particles carrying mobile and fixed ligands.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Ruben Agustin-Panadero, Blanca Serra-Pastor, Ignazio Loi, M. Jesus Suarez, Jesus Pelaez, Fernanda Sola-Ruiz
Summary: This study evaluated the clinical, mechanical, and biological behavior of posterior 3-unit fixed partial dentures (FPDs) prepared using BOPT technique. The results showed that the BOPT group had better outcomes in terms of plaque index, gingival index, probing depth, and marginal stability compared to the control group, indicating predictable and positive results after 5 years of follow-up.
JOURNAL OF PROSTHETIC DENTISTRY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Naomi Tanoue, Hideo Matsumura, Tetsuo Yamamori, Shuji Ohkawa
Summary: This review evaluated the survival rate of resin-bonded fixed partial dentures (RBFPDs) made of metal alloys, finding that the survival rate depended on the type of metal alloy, adhesion system, and observation period assessed.
JOURNAL OF PROSTHODONTIC RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Nouf Almeganni, Rotana Abulaban, Ghada Naguib, Mohamed Tharwat, Hani M. Nassar
Summary: The purpose of this study was to analyze the stress distribution of fiber-reinforced composite provisional fixed partial denture using a finite element analysis model. Three anterior teeth were collected and a fiber-reinforced composite strip was applied to their palatal surfaces. Micro-computed tomographic scans were used to generate three-dimensional replicas, and finite element analysis was conducted to assess the stress distribution. The results showed that using unprepared natural tooth pontic in the anterior provisional fixed partial denture is superior in terms of stress distribution.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2023)
Article
Chemistry, Physical
Fernando Garcia-Sala Bonmati, Naia Bustamante-Hernandez, Jorge Alonso Perez-Barquero, Jesus Maneiro-Lojo, Carla Fons-Badal, Carla Labaig-Caturla, Lucia Fernandez-Estevan, Ruben Agustin-Panadero
Summary: This study analyzed the mechanical behavior of different types of fixed partial dentures with posterior cantilevers on dental implants. The results showed that directly screw-retained prostheses had the highest strength value, while the other connection types had relatively lower strength values. These findings are important for the selection and design of implant-borne prostheses.
Article
Polymer Science
Larissa Mendes Campaner, Marcos Paulo Motta Silveira, Guilherme Schmitt de Andrade, Alexandre Luiz Souto Borges, Marco Antonio Bottino, Amanda Maria de Oliveira Dal Piva, Roberto Lo Giudice, Pietro Ausiello, Joao Paulo Mendes Tribst
Summary: This study evaluated the biomechanical behavior of different interim restorative materials for posterior fixed partial dentures, with resin composite attenuating stress on the cement layer and acrylic resin attenuating stress on the connector region.
Review
Dentistry, Oral Surgery & Medicine
Paolo Francesco Manicone, Paolo De Angelis, Edoardo Rella, Giovanni Damis, Antonio D'addona
Summary: Digital scanning has been found to be more time-efficient and preferred by patients for implant-supported restorations compared to conventional impression making.
JOURNAL OF PROSTHETIC DENTISTRY
(2022)
Article
Chemistry, Analytical
Sabrina Romano, Flavio Di Giacinto, Aniello Primiano, Jacopo Gervasoni, Alberto Mazzini, Massimiliano Papi, Andrea Urbani, Annalucia Serafino, Marco De Spirito, Ewa K. Krasnowska, Gabriele Ciasca
Summary: FTIR spectroscopy is an effective method for studying the differences in cancer-derived EXOs from different cell phenotypes, providing possibilities for diagnosis. The spectral features of EXOs derived from different cell phenotypes in the infrared range can be used to monitor cell changes effectively.
ANALYTICA CHIMICA ACTA
(2022)
Review
Chemistry, Physical
Benedetta Niccolini, Valentina Palmieri, Marco De Spirito, Massimiliano Papi
Summary: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron degeneration, and deregulation of miRNAs is critical for its onset. Recent studies have focused on the design of delivery systems, such as graphene, to correct aberrant miRNA expression, providing a primer for future research in this field.
Article
Archaeology
Lorenzo Teodonio, Claudia Scatigno, Mauro Missori, Giulia Festa
Summary: This article investigates watermarked papers from the Late Middle Ages in Italy, using machine learning and spectroscopy techniques to analyze the data and trace the fabrication recipes and geographical production of paper mills. The results show that watermarked papers from Northern Italy and Bologna have similar compositions, potentially influenced by local hand-made processing techniques and technological exchange between cities.
JOURNAL OF CULTURAL HERITAGE
(2022)
Article
Materials Science, Textiles
Flavio De Maio, Giulia Santarelli, Valentina Palmieri, Giordano Perini, Alessandro Salustri, Ivana Palucci, Giovanni Delli Carpini, Alberto Augello, Maurizio Sanguinetti, Marco De Spirito, Michela Sali, Giovanni Delogu, Massimiliano Papi
Summary: Respiratory tract infections are the leading cause of death from infectious diseases globally, with COVID-19 adding to the burden of existing respiratory tract infections like tuberculosis. Graphene and curcumin can be used to create fabric coatings on cotton and polyester, providing personal protective equipment that is resistant to infectious agents.
JOURNAL OF NATURAL FIBERS
(2023)
Article
Biochemistry & Molecular Biology
Giada Bianchetti, Maria Elisabetta Clementi, Beatrice Sampaolese, Cassandra Serantoni, Alessio Abeltino, Marco De Spirito, Shlomo Sasson, Giuseppe Maulucci
Summary: Diabetes-induced oxidative stress causes vascular complications, particularly diabetic retinopathy (DR), which is attributed to harmful oxidative stress events in the blood-retinal barrier (BRB). Docosahexaenoic acid (DHA) has therapeutic potential against oxidative damage in retinal pigment epithelium cells (ARPE-19) and activates the Nrf2/Nqo1 signaling cascade to promote antioxidant response. This study investigates the modulation of lipid metabolism by high-glucose (HG) conditions on ARPE-19 cells and demonstrates that DHA ameliorates lipid metabolism and reduces ROS production under HG conditions. Targeting lipid metabolism pathways may offer new treatment strategies for DR.
Article
Chemistry, Physical
Valentina Palmieri, Francesco Amato, Andrea Giacomo Marrani, Ginevra Friggeri, Giordano Perini, Alberto Augello, Marco De Spirito, Massimiliano Papi
Summary: Graphene Oxide (GO) is an oxidized form of graphene that contains various oxygen functional groups. The solubility of GO in water makes it an ideal material in the biomedical field, but the synthesis methods used can affect the balance of oxygen groups and the impact on cells. Spectroscopic techniques are commonly used to characterize GO, but they have limitations in indicating its reactivity with polymers or biological media. In this study, a colorimetric method based on GO's reactivity with copper ions was developed to evaluate the oxidation degree and accessibility of polymeric samples. This technique will be crucial for scaffold characterization in tissue engineering and studying interactions between GO-related materials and biological entities.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Physical
Massimiliano Papi, Marco De Spirito, Valentina Palmieri
Summary: The COVID-19 pandemic has prompted collaboration between nanotechnology scientists, industry stakeholders, and clinicians to find solutions for SARS-CoV-2 infections. Carbon-based materials (CBM) like graphene and carbon nanotubes have shown potential in viral research due to their unique effects on microorganisms and immune interaction. This review explores the interaction of CBM with SARS-CoV-2, including their physical and chemical properties, known interactions with viral components, and potential applications in prevention, treatment, and diagnostics.
Article
Optics
Laura Pilozzi, Mauro Missori, Claudio Conti
Summary: In this study, the transition from Fano resonances to Bound states in the continuum (BIC) in a one-dimensional photonic crystal slab made of rectangular dielectric rods was investigated at terahertz frequencies. Symmetry-protected, high-Q BIC were found at normal incidence through simulations based on an analytical exact solution of the Maxwell equations. For non-normal incidence, BIC coupled with freely propagating waves and appeared as Fano resonances in the scattering field. The simulations were validated by 3D-printing the photonic crystal slab and comparing THz time-domain spectroscopy measurements.
Article
Nutrition & Dietetics
Alessio Abeltino, Giada Bianchetti, Cassandra Serantoni, Alessia Riente, Marco De Spirito, Giuseppe Maulucci
Summary: Nutrition is a crucial aspect of medicine, affecting various health conditions. Digital medicine utilizes digital twins, which are replicas of human physiology, to prevent and treat diseases. This study compared different models for the deployment of Personalized Metabolic Avatars, with GRUs and LSTMs showing the best predictive performance and acceptable computational times. The Transformer model did not significantly improve predictive performance but increased computational time, while the SARIMAX model had the best computational time but worst predictive performance.
Article
Health Care Sciences & Services
Edoardo Rella, Paolo De Angelis, Laura Papetti, Giovanni Damis, Antonio D'Addona, Paolo Francesco Manicone
Summary: The study aimed to evaluate the impact of using a two implants mandibular overdenture on the quality of life of edentulous patients. The results showed that even after one month of treatment, there was an improvement in the patients' quality of life, which remained stable at the one-year follow-up.
Article
Multidisciplinary Sciences
Davide Pierangeli, Giordano Perini, Valentina Palmieri, Ivana Grecco, Ginevra Friggeri, Marco De Spirito, Massimiliano Papi, Eugenio DelRe, Claudio Conti
Summary: The authors discovered that tumor-cell spheroids exhibit optical rogue waves under randomly modulated laser beam illumination. The intensity of transmitted light follows a Weibull statistical distribution, with extreme events corresponding to localized optical modes propagating within the cell network. These nonlinear optical filaments form high-transmission channels and can be used to achieve controlled temperature increase. This study sheds light on optical propagation in biological aggregates and demonstrates the potential of using rogue waves in biomedical applications.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Francesco Amato, Giordano Perini, Ginevra Friggeri, Alberto Augello, Alessandro Motta, Leonardo Giaccari, Robertino Zanoni, Marco De Spirito, Valentina Palmieri, Andrea Giacomo Marrani, Massimiliano Papi
Summary: Graphene oxide and reduced graphene oxide are widely used carbon nanomaterials in biomedicine. However, the hydrophobic behavior of reduced graphene oxide limits its stability in biological media. In this study, sodium ascorbate is used as a reducing agent to prepare reduced graphene oxide with improved stability and suitability for applications in cell culture media.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Chemistry, Analytical
Alessia Riente, Alessio Abeltino, Cassandra Serantoni, Giada Bianchetti, Marco De Spirito, Stefano Capezzone, Rosita Esposito, Giuseppe Maulucci
Summary: We developed a non-invasive device that evaluates personalized chewing styles by analyzing various aspects. The device provides valuable insights into personalized chewing profiles and could modify unhealthy chewing habits.
Article
Chemistry, Physical
Lorenzo Gontrani, Elvira Maria Bauer, Alessandro Talone, Mauro Missori, Patrizia Imperatori, Pietro Tagliatesta, Marilena Carbone
Summary: The report investigates the relationship between synthesis methods and the size and morphology of copper oxide nanoparticles. It is found that hydrothermal synthesis without surfactants leads to spheroidal dandelion-like aggregates, while the addition of surfactants promotes directional growth of nanostructures. The structure and properties of the nanoparticles are studied using powder X-ray diffraction, scanning electron microscopy, and diffuse reflectance spectroscopy. The effect of morphology on electronic properties is evaluated using DRS, and the results are compared with computational models.