Article
Mathematics
Marin Marin, Aatef Hobiny, Ibrahim Abbas
Summary: In this work, numerical estimations for a nonlinear hyperbolic bioheat equation were constructed for medicinal treatments of tumor cells. The study considered the experimental temperature-dependent functions of heating source components in the model. The finite element method was used to solve the nonlinear problem, and parametric analysis was conducted to enhance the accuracy of thermal power in hyperthermia treatments.
Article
Thermodynamics
P. H. Zhao, K. Li, H. Zhang, D. Li, B. Chen, Y. P. Zheng, W. P. Li, G. X. Wang, L. H. Fan, L. Yao
Summary: A coupled whole-eye model for retinal laser surgery was developed, which simulated the thermal responses of the eye during several laser retinal surgery processes at different time scales. The model was also applied in a real fundus anatomy from a patient with diabetic retinopathy to demonstrate its feasibility in customized laser protocol planning.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2023)
Article
Computer Science, Interdisciplinary Applications
A. Bera, S. Dutta, J. C. Misra, G. C. Shit
Summary: This paper develops a mathematical model to investigate the effects of dual-phase lag on tumor tissue heating protocol. Experimental results show that the phase lag caused by heat flux is more effective.
MATHEMATICS AND COMPUTERS IN SIMULATION
(2021)
Article
Computer Science, Interdisciplinary Applications
Amritpal Singh, Neeraj Kumar
Summary: This study uses the finite-volume immersed boundary method (FV-IBM) to solve bioheat physics in actual liver tumor tissue, achieving the boundary effect on the non-body conformal Cartesian grid using the IBM technique. The FV-IBM scheme has been validated and shown to have second-order accuracy. Results for the hyperthermia investigation in liver tumor with different heat source distributions are in good agreement with COMSOL Multiphysics simulation. This proposed FV-IBM-based numerical scheme provides a simple and robust method for solving bioheat models in arbitrary tissue shapes.
ENGINEERING WITH COMPUTERS
(2023)
Article
Biology
P. Michaux, B. Gaume, Y. Cong, O. Quemener
Summary: This article presents the development of a digital twin model for the thigh portion undergoing various thermal treatments. Two scenarios, cold water immersion (CWI) and whole body cryotherapy (WBC), are investigated and the numerical results are validated against experimental measurements. The use of real geometry on a first subject demonstrates the heterogeneity of the temperature field and the importance of accurate geometry. A second subject with thicker adipose tissue highlights the impact of the subject's actual morphology on treatment validity and the need for real geometry to optimize cold modalities and develop personalized treatments.
COMPUTERS IN BIOLOGY AND MEDICINE
(2024)
Article
Computer Science, Interdisciplinary Applications
Bruna R. Loiola, Francesco Scofano Neto, Rodrigo O. C. Guedes
Summary: This study presents a numerical analysis of the Duodenal Mucosal Resurfacing (DMR) technique for Type 2 diabetes treatment, showing that the treatment can accurately target cells in the mucosal layer without affecting the outermost stratum of the organ when lifting of the mucosal duodenum layer is achieved. However, caution should be taken by physicians for the case without lifting, as the muscularis propria layer may reach temperatures above 42 degrees C during a short time interval.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Mathematics, Interdisciplinary Applications
Nehad Ali Shah, Bander Almutairi, Dumitru Vieru, Beomseon Lee, Jae Dong Chung
Summary: This article investigates the effects of thermal memory and the moving line thermal shock on heat transfer in biological tissues using a generalized form of the Pennes equation. A novel time-fractional generalized Fourier's law is used to build the mathematical model, which considers the temperature gradient as well as its historical behavior. Numerical simulations and graphic representations analyze the influence of the thermal memory parameter on heat transfer.
FRACTAL AND FRACTIONAL
(2023)
Article
Mechanics
Tareq Saeed, Ibrahim Abbas
Summary: This study investigates the transient phenomena in a spherical tissue caused by a laser heat source using mathematical models based on the non-linear dual phase lag model. The finite element method is adopted to obtain the solutions of this problem due to the nonlinearity of the basic equations. The numerical results obtained by the finite element method are compared with experimental data to verify their accuracy, and the comparison demonstrates the effectiveness of the existing mathematical model in estimating the bio-heat model in spherical biological tissues.
MECHANICS BASED DESIGN OF STRUCTURES AND MACHINES
(2022)
Article
Thermodynamics
E. Y. K. Ng, E. Y. L. Pang
Summary: This study employed coupled CFD and CHT simulations to investigate the impact of pulsatile blood flow through the infrarenal aorta on the temperature distribution of the midriff skin, finding a thermal elevation on the abdomen surface for AAA cases. Experiment validation showed similar thermal trends, suggesting potential for Infrared Thermography as a diagnostic tool for AAA.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2022)
Article
Computer Science, Interdisciplinary Applications
Assunta Andreozzi, Luca Brunese, Marcello Iasiello, Claudio Tucci, Giuseppe Peter Vanoli
Summary: This paper analyzes the effects of pulsating heat in tumor tissue under hyperthermia, finding that pulsatile heat protocols can decrease maximum temperature and achieve the same treatment outcomes as non-pulsating heat sources.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Mathematical & Computational Biology
Ewa Majchrzak, Mikolaj Stryczynski
Summary: This study investigates the influence of heating techniques on temperature distribution in a blood vessel surrounded by biological tissue with a tumor, considering dual-phase lag equations to describe the process. The problem is solved using the implicit scheme of the finite difference method.
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2021)
Article
Physics, Multidisciplinary
Faris S. Alzahrani, Ibrahim A. Abbas
Summary: This study presents analytical solutions for the dual-phase-lag bioheat equation to treat cancer cells, considering volumetric thermal source components and obtaining solutions in the Laplace domain. Thermal injuries to tissues are assessed using the Arrhenius formulation, with numerical temperature outcomes graphically presented. A parametric analysis is used to identify important design variables for predicting accurate heating in hyperthermia treatment.
WAVES IN RANDOM AND COMPLEX MEDIA
(2021)
Article
Computer Science, Interdisciplinary Applications
Manpreet Singh, Tulika Singh, Sanjeev Soni
Summary: The study evaluates the effects of heat deposition rate, exposure duration, and blood perfusion metrics on patient-specific breast tumor models. It shows that treatment margins smaller than 5 mm are sufficient, with heating beyond 3 mm causing higher damage surrounding the tumor. Highly perfused tumors require more heat dosage and longer treatment duration compared to moderately perfused tumors for successful thermal ablation.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Engineering, Chemical
John Gorman, Winston Tan, John Abraham
Summary: This study numerically modeled a microwave ablation probe and validated the numerical approach with experimental data. The results can be used to predict tissue damage caused by microwave ablation procedures.
Article
Thermodynamics
Assunta Andreozzi, Luca Brunese, Marcello Iasiello, Claudio Tucci, Giuseppe Peter Vanoli
Summary: In this study, improved bioheat models were used to investigate the thermal ablation treatment for liver cancer. By incorporating factors such as variable porosity and perfusion, the accuracy of the model was enhanced. Numerical results showed that the modified porous media-based model had a good agreement with the actual measurements, providing valuable insights for improving thermal ablation modeling.
THERMAL SCIENCE AND ENGINEERING PROGRESS
(2022)
