Structure and dynamics of Helicobacter pylori nickel-chaperone HypA: an integrated approach using NMR spectroscopy, functional assays and computational tools

The Helicobacter pylori HypA·UreE2 Complex Contains a Novel High-Affinity Ni(II)-Binding Site

(2018) Heidi Q. Hu et al.   BIOCHEMISTRY

Crystal structures of a [NiFe] hydrogenase large subunit HyhL in an immature state in complex with a Ni chaperone HypA

(2018) Sunghark Kwon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acid-responsive activity of theHelicobacter pylorimetalloregulator NikR

(2018) Michael D. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-function analyses of metal-binding sites of HypA reveal residues important for hydrogenase maturation in Helicobacter pylori

(2017) Faith C. Blum et al.   PLoS One

The Immune Battle against Helicobacter pylori Infection: NO Offense

(2016) Alain P. Gobert et al.   TRENDS IN MICROBIOLOGY

Transient iron coordination sites in proteins: Exploiting the dual nature of paramagnetic NMR

(2015) Mario Piccioli et al.   COORDINATION CHEMISTRY REVIEWS

Improved reliability, accuracy and quality in automated NMR structure calculation with ARIA

(2015) Fabien Mareuil et al.   JOURNAL OF BIOMOLECULAR NMR

Dynamic HypA zinc site is essential for acid viability and proper urease maturation in Helicobacter pylori

(2015) Ryan C. Johnson et al.   Metallomics

Structural basis of a Ni acquisition cycle for [NiFe] hydrogenase by Ni-metallochaperone HypA and its enhancer

(2015) Satoshi Watanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SPECTRUS: A Dimensionality Reduction Approach for Identifying Dynamical Domains in Protein Complexes from Limited Structural Datasets

(2015) Luca Ponzoni et al.   STRUCTURE

YASARA View—molecular graphics for all devices—from smartphones to workstations

(2014) Elmar Krieger et al.   BIOINFORMATICS

Nickel Free-Diet Enhances the Helicobacter pylori Eradication Rate: A Pilot Study

(2014) M. Campanale et al.   DIGESTIVE DISEASES AND SCIENCES

Epidemiology ofHelicobacter pyloriInfection

(2014) Leonardo H. Eusebi et al.   HELICOBACTER

Nickel translocation between metallochaperones HypA and UreE in Helicobacter pylori

(2014) Xinming Yang et al.   Metallomics

Beyond the stomach: An updated view ofHelicobacter pyloripathogenesis, diagnosis, and treatment

(2014) Traci L Testerman   WORLD JOURNAL OF GASTROENTEROLOGY

Nonredox Nickel Enzymes

(2013) Michael J. Maroney et al.   CHEMICAL REVIEWS

Biosynthesis of the Urease Metallocenter

(2013) Mark A. Farrugia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Structure of UreG/UreF/UreH Complex Reveals How Urease Accessory Proteins Facilitate Maturation of Helicobacter pylori Urease

(2013) Yu Hang Fong et al.   PLOS BIOLOGY

H++ 3.0: automating pK prediction and the preparation of biomolecular structures for atomistic molecular modeling and simulations

(2012) R. Anandakrishnan et al.   NUCLEIC ACIDS RESEARCH

Chemistry of Ni2+in Urease: Sensing, Trafficking, and Catalysis

(2011) Barbara Zambelli et al.   ACCOUNTS OF CHEMICAL RESEARCH

Crystallographic and X-ray absorption spectroscopic characterization ofHelicobacter pyloriUreE bound to Ni2+and Zn2+reveals a role for the disordered C-terminal arm in metal trafficking

(2011) Katarzyna Banaszak et al.   BIOCHEMICAL JOURNAL

Suppression of sampling artefacts in high-resolution four-dimensional NMR spectra using signal separation algorithm

(2011) Jan Stanek et al.   JOURNAL OF MAGNETIC RESONANCE

The ORCA program system

(2011) Frank Neese   Wiley Interdisciplinary Reviews-Computational Molecular Science

Treatment of gastric marginal zone lymphoma of MALT type

(2010) Anastasios Stathis et al.   EXPERT OPINION ON PHARMACOTHERAPY

Structural Survey of Zinc-Containing Proteins and Development of the Zinc AMBER Force Field (ZAFF)

(2010) Martin B. Peters et al.   Journal of Chemical Theory and Computation

Communication between the Zinc and Nickel Sites in Dimeric HypA: Metal Recognition and pH Sensing

(2010) Robert W. Herbst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms of disease: Helicobacter pylori virulence factors

(2010) Yoshio Yamaoka   Nature Reviews Gastroenterology & Hepatology

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

A microscale protein NMR sample screening pipeline

(2009) Paolo Rossi et al.   JOURNAL OF BIOMOLECULAR NMR

Crystal Structure of HypA, a Nickel-Binding Metallochaperone for [NiFe] Hydrogenase Maturation

(2009) Satoshi Watanabe et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a Nickel Chaperone, HypA, from Helicobacter pylori Reveals Two Distinct Metal Binding Sites

(2009) Wei Xia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8

(2009) Elmar Krieger et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Accurate NMR Structures Through Minimization of an Extended Hybrid Energy

(2008) Michael Nilges et al.   STRUCTURE