Mammalian metallothionein in toxicology, cancer, and cancer chemotherapy

The intracellular redox stress caused by hexavalent chromium is selective for proteins that have key roles in cell survival and thiol redox control

(2011) Judith M. Myers et al.   TOXICOLOGY

Nitric oxide and zinc homeostasis in pulmonary endothelium

(2010) Huihua Li et al.   Annals of the New York Academy of Sciences

Zinc Finger Transcription Factor Zn3-Sp1 Reactions with Cd2+

(2010) Rajendra Kothinti et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Reactivity of Zn-, Cd-, and Apo-Metallothionein with Nitric Oxide Compounds: In Vitro and Cellular Comparison

(2010) Jianyu Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Adverse Effects of Methylmercury: Environmental Health Research Implications

(2010) Philippe Grandjean et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mechanism of Cadmium Ion Substitution in Mammalian Zinc Metallothionein and Metallothionein α Domain: Kinetic and Structural Studies

(2010) John Ejnik et al.   INORGANIC CHEMISTRY

Involvement of metallothionein (MT) as a biological protective factor against carcinogenesis induced by benzo[a]pyrene (B[a]P)

(2010) Masaki Takaishi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Metallothioneins: unparalleled diversity in structures and functions for metal ion homeostasis and more

(2010) Claudia A. Blindauer et al.   NATURAL PRODUCT REPORTS

Arsenolysis and Thiol-Dependent Arsenate Reduction

(2010) David J. Thomas   TOXICOLOGICAL SCIENCES

Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice

(2010) Erik J. Tokar et al.   TOXICOLOGY

Cadmium down-regulation of kidney Sp1 binding to mouse SGLT1 and SGLT2 gene promoters: Possible reaction of cadmium with the zinc finger domain of Sp1

(2010) Rajendra K. Kothinti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Enhanced toxicity and ROS generation by doxorubicin in primary cultures of cardiomyocytes from neonatal metallothionein-I/II null mice

(2010) Ze Fu et al.   TOXICOLOGY IN VITRO

Systemic zinc redistribution and dyshomeostasis in cancer cachexia

(2010) Pontus M. A. Siren et al.   Journal of Cachexia Sarcopenia and Muscle

The Chemical Forms of Mercury in Aged and Fresh Dental Amalgam Surfaces

(2009) Graham N. George et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oral exposure to inorganic arsenic: evaluation of its carcinogenic and non-carcinogenic effects

(2009) Ulrike Schuhmacher–Wolz et al.   CRITICAL REVIEWS IN TOXICOLOGY

Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma

(2009) Klaus Jürgen Schmitz et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Induction of Metallothionein I by Arsenic via Metal-activated Transcription Factor 1

(2009) Xiaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reaction of the zinc sensor FluoZin-3 with Zn7-metallothionein: Inquiry into the existence of a proposed weak binding site

(2009) Mohammad Ali Namdarghanbari et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Potential Role of α-Synuclein and Metallothionein in Lead-Induced Inclusion Body Formation

(2009) Peijun Zuo et al.   TOXICOLOGICAL SCIENCES

Metallothionein protection of cadmium toxicity

(2009) Curtis D. Klaassen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Historical perspectives on cadmium toxicology

(2009) Gunnar F. Nordberg   TOXICOLOGY AND APPLIED PHARMACOLOGY

Noncooperative cadmium(II) binding to human metallothionein 1a

(2008) Duncan E.K. Sutherland et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BCNU-sequestration by metallothioneins may contribute to resistance in a medulloblastoma cell line

(2008) Manny D. Bacolod et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Mitochondrial Protein Targets of Thiol-Reactive Electrophiles

(2008) Hansen L. Wong et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Emergence of Delayed Methylmercury Toxicity after Perinatal Exposure in Metallothionein-Null and Wild-Type C57BL Mice

(2008) Minoru Yoshida et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Role of metallothionein in lung inflammation induced by ozone exposure in mice

(2008) Ken-ichiro Inoue et al.   FREE RADICAL BIOLOGY AND MEDICINE

Over-expression of metallothionein predicts chemoresistance in breast cancer

(2008) Xinli Yap et al.   JOURNAL OF PATHOLOGY

Kinetic Analysis of Arsenic−Metalation of Human Metallothionein: Significance of the Two-Domain Structure

(2008) Thanh T. Ngu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of metallothionein as a protective factor against radiation carcinogenesis

(2008) Kiyoshi Shibuya et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal

(2008) Simona G. Codreanu et al.   MOLECULAR & CELLULAR PROTEOMICS

Glutathione: Overview of its protective roles, measurement, and biosynthesis

(2008) Henry Jay Forman et al.   MOLECULAR ASPECTS OF MEDICINE

Mercury-induced cognitive impairment in metallothionein-1/2 null mice

(2008) Donnie Eddins et al.   NEUROTOXICOLOGY AND TERATOLOGY

The role of metallothionein in oncogenesis and cancer prognosis

(2008) Mie Ø. Pedersen et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Zinc binding ligands and cellular zinc trafficking: Apo-metallothionein, glutathione, TPEN, proteomic zinc, and Zn-Sp1

(2007) Ujala Rana et al.   JOURNAL OF INORGANIC BIOCHEMISTRY