Metallothionein and brain inflammation

Murine models of Alzheimer's disease and their use in developing immunotherapies

(2010) Thomas Wisniewski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

(2010) Koen Bossers et al.   BRAIN

Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain

(2010) Claire Howells et al.   FEBS Journal

Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin

(2010) Ana Martinho et al.   FEBS Journal

Reimagining Alzheimer's Disease--An Age-Based Hypothesis

(2010) K. Herrup   JOURNAL OF NEUROSCIENCE

Zinc release of Zn7-metallothionein-3 induces fibrillar type amyloid-β aggregates

(2010) Jade Durand et al.   Metallomics

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Probing the Biology of Alzheimer's Disease in Mice

(2010) Karen H. Ashe et al.   NEURON

The Genetics of Alzheimer Disease: Back to the Future

(2010) Lars Bertram et al.   NEURON

The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated Aβ Aggregation and Toxicity in Rat Cortical Neurons

(2010) Roger S. Chung et al.   PLoS One

Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics

(2010) James A. Duce et al.   PROGRESS IN NEUROBIOLOGY

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

(2009) Nathan R. Rustay et al.   BRAIN RESEARCH

Metallothionein induces a regenerative reactive astrocyte phenotype via JAK/STAT and RhoA signalling pathways

(2009) Y.K.J. Leung et al.   EXPERIMENTAL NEUROLOGY

Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effectin vivo

(2009) Cristina Lanza et al.   JOURNAL OF NEUROCHEMISTRY

Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-β (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators

(2009) Vello Tõugu et al.   JOURNAL OF NEUROCHEMISTRY

Autoimmunity: increasing suspects in the CD4+ T cell lineup

(2009) Matthew T Palmer et al.   NATURE IMMUNOLOGY

Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease

(2009) Tania García et al.   TOXICOLOGY

Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary fibrosis in rats

(2008) Gouda Kamel Helal et al.   ARCHIVES OF TOXICOLOGY

Transthyretin Interacts with Metallothionein 2†

(2008) I. Gonçalves et al.   BIOCHEMISTRY

Infection of metallothionein 1+2 knockout mice with Rocky Mountain Laboratory scrapie

(2008) Enric Vidal et al.   BRAIN RESEARCH

The Metallothionein/Thionein System: An Oxidoreductive Metabolic Zinc Link

(2008) Stephen G. Bell et al.   CHEMBIOCHEM

Microglia

(2008) Denis Soulet et al.   CURRENT BIOLOGY

A calculated response: control of inflammation by the innate immune system

(2008) Gregory M. Barton   JOURNAL OF CLINICAL INVESTIGATION

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Metal swap between Zn7-metallothionein-3 and amyloid-β–Cu protects against amyloid-β toxicity

(2008) Gabriele Meloni et al.   Nature Chemical Biology

Can the immune system be harnessed to repair the CNS?

(2008) Phillip G. Popovich et al.   NATURE REVIEWS NEUROSCIENCE

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

(2008) Paul A. Adlard et al.   NEURON

Metallothionein in the central nervous system: Roles in protection, regeneration and cognition

(2008) Adrian K. West et al.   NEUROTOXICOLOGY

Exogenous metallothionein-IIA promotes accelerated healing after a burn wound

(2008) Natalie M. Morellini et al.   WOUND REPAIR AND REGENERATION

Structural Biology of Shared Cytokine Receptors

(2007) Xinquan Wang et al.   Annual Review of Immunology

Effect of astrocyte-targeted production of IL-6 on traumatic brain injury and its impact on the cortical transcriptome

(2007) Albert Quintana et al.   Developmental Neurobiology