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Title
Allosteric Inhibition of Epac
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 42, Pages 29148-29157
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-09-03
DOI
10.1074/jbc.m114.569319
References
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Related references
Note: Only part of the references are listed.- Identification and Validation of Modulators of Exchange Protein Activated by cAMP (Epac) Activity
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- cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane
- (2012) S. V. Consonni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice
- (2012) Deepak P. Srivastava et al. PLOS BIOLOGY
- Cyclic AMP Control Measured in Two Compartments in HEK293 Cells: Phosphodiesterase KM Is More Important than Phosphodiesterase Localization
- (2011) Karina Matthiesen et al. PLoS One
- Structural conservation of druggable hot spots in protein-protein interfaces
- (2011) D. Kozakov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- I-TASSER: a unified platform for automated protein structure and function prediction
- (2010) Ambrish Roy et al. Nature Protocols
- Epac increases melanoma cell migration by a heparan sulfate-related mechanism
- (2009) Erdene Baljinnyam et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques
- (2009) Ryan Brenke et al. BIOINFORMATICS
- Mechanism of Epac Activation
- (2009) Tamara Tsalkova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The cAMP/Epac1/Rap1 Pathway in Pancreatic Carcinoma
- (2009) Richard Lorenz et al. PANCREAS
- I-TASSER server for protein 3D structure prediction
- (2008) Yang Zhang BMC BIOINFORMATICS
- Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells
- (2008) Motonori Takahashi et al. GENES TO CELLS
- Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP
- (2008) Rahul Das et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2
- (2008) C. Liu et al. MOLECULAR AND CELLULAR BIOLOGY
- Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
- (2008) Holger Rehmann et al. NATURE
- The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals
- (2008) U. Yokoyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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