3-Deazaneplanocin A (DZNep), an Inhibitor ofS-Adenosylmethionine-dependent Methyltransferase, Promotes Erythroid Differentiation
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Title
3-Deazaneplanocin A (DZNep), an Inhibitor ofS-Adenosylmethionine-dependent Methyltransferase, Promotes Erythroid Differentiation
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 12, Pages 8121-8134
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-02-04
DOI
10.1074/jbc.m114.548651
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- (2010) Marc A. Kerenyi et al. JOURNAL OF EXPERIMENTAL MEDICINE
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