A Role for Stefin B (Cystatin B) in Inflammation and Endotoxemia

Decreased IL-10 expression in stefin B-deficient macrophages is regulated by the MAP kinase and STAT-3 signaling pathways

(2014) Katarina Maher et al.   FEBS LETTERS

Mitochondria-targeted drugs enhance Nlrp3 inflammasome-dependent IL-1β secretion in association with alterations in cellular redox and energy status

(2013) Joshua Jabaut et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model

(2013) M Butinar et al.   ONCOGENE

Noncanonical Inflammasomes: Caspase-11 Activation and Effector Mechanisms

(2013) Petr Broz et al.   PLoS Pathogens

Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines

(2012) Aleš Špes et al.   BIOLOGICAL CHEMISTRY

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

(2012) Terry C. Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics

(2012) Maxim Nekrasov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stage and Gene Specific Signatures Defined by Histones H3K4me2 and H3K27me3 Accompany Mammalian Retina Maturation In Vivo

(2012) Evgenya Y. Popova et al.   PLoS One

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mitochondria: Sovereign of inflammation?

(2011) Jürg Tschopp   EUROPEAN JOURNAL OF IMMUNOLOGY

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release

(2011) Tobias Hoegen et al.   JOURNAL OF IMMUNOLOGY

Expression of Innate and Adaptive Immune Mediators in Human Corneal Tissue Infected With Aspergillus or Fusarium

(2011) Rajapandian Sivaganesa Karthikeyan et al.   JOURNAL OF INFECTIOUS DISEASES

Early Microglial Activation Precedes Neuronal Loss in the Brain of theCstb−/−Mouse Model of Progressive Myoclonus Epilepsy, EPM1

(2011) Saara Tegelberg et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inhibition of interferon response by cystatin B: implication in HIV replication of macrophage reservoirs

(2011) L. Rivera-Rivera et al.   JOURNAL OF NEUROVIROLOGY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Stefin B Interacts with Histones and Cathepsin L in the Nucleus

(2010) Slavko Čeru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X7 Receptor-Mediated Release of Cathepsins from Macrophages Is a Cytokine-Independent Mechanism Potentially Involved in Joint Diseases

(2010) G. Lopez-Castejon et al.   JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Granulysin Induces Cathepsin B Release from Lysosomes of Target Tumor Cells to Attack Mitochondria through Processing of Bid Leading to Necroptosis

(2009) H. Zhang et al.   JOURNAL OF IMMUNOLOGY

Cystatin B Deficiency Sensitizes Neurons to Oxidative Stress in Progressive Myoclonus Epilepsy, EPM1

(2009) M. K. Lehtinen et al.   JOURNAL OF NEUROSCIENCE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Cystatin B Associates with Signal Transducer and Activator of Transcription 1 in Monocyte-Derived and Placental Macrophages

(2009) C. Luciano-Montalvo et al.   PLACENTA

Cathepsin L Proteolytically Processes Histone H3 During Mouse Embryonic Stem Cell Differentiation

(2008) Elizabeth M. Duncan et al.   CELL

Cystatins: Biochemical and structural properties, and medical relevance

(2008) ">Vito Turk   Frontiers in Bioscience-Landmark

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Molecular background of EPM1—Unverricht–Lundborg disease

(2007) Tarja Joensuu et al.   EPILEPSIA