Development and Characterization of Pepducins as Gs-biased Allosteric Agonists
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Development and Characterization of Pepducins as Gs-biased Allosteric Agonists
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 52, Pages 35668-35684
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-11-14
DOI
10.1074/jbc.m114.618819
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Minireview: More Than Just a Hammer: Ligand “Bias” and Pharmaceutical Discovery
- (2014) Louis M. Luttrell MOLECULAR ENDOCRINOLOGY
- Contemporary Use of β-Blockers: Clinical Relevance of Subclassification
- (2013) Luc Poirier et al. CANADIAN JOURNAL OF CARDIOLOGY
- The Dynamic Process of β2-Adrenergic Receptor Activation
- (2013) Rie Nygaard et al. CELL
- Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking
- (2013) Dong Soo Kang et al. CURRENT OPINION IN CELL BIOLOGY
- Interactions of the α-subunits of heterotrimeric G-proteins with GPCRs, effectors and RGS proteins: A critical review and analysis of interacting surfaces, conformational shifts, structural diversity and electrostatic potentials
- (2013) Fotis A. Baltoumas et al. JOURNAL OF STRUCTURAL BIOLOGY
- The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist
- (2013) Catherine E. Erickson et al. PLoS One
- Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein
- (2013) J. Quoyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Turning Receptors On and Off with Intracellular Pepducins: New Insights into G-protein-coupled Receptor Drug Development
- (2012) Katie O'Callaghan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biased Signaling Pathways in 2-Adrenergic Receptor Characterized by 19F-NMR
- (2012) J. J. Liu et al. SCIENCE
- Ligand-Specific Interactions Modulate Kinetic, Energetic, and Mechanical Properties of the Human β2 Adrenergic Receptor
- (2012) Michael Zocher et al. STRUCTURE
- β2-adrenoceptor agonists: current and future direction
- (2011) Mario Cazzola et al. BRITISH JOURNAL OF PHARMACOLOGY
- Structure of a nanobody-stabilized active state of the β2 adrenoceptor
- (2011) Søren G. F. Rasmussen et al. NATURE
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Age and Risks of FDA-Approved Long-Acting 2-Adrenergic Receptor Agonists
- (2011) A. W. McMahon et al. PEDIATRICS
- Activation mechanism of the 2-adrenergic receptor
- (2011) R. O. Dror et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct Phosphorylation Sites on the 2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of -Arrestin
- (2011) K. N. Nobles et al. Science Signaling
- Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling
- (2011) Jillian G. Baker et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Activation of human monocytes by a formyl peptide receptor 2-derived pepducin
- (2010) Ha Young Lee et al. FEBS LETTERS
- 20-HETE Mediates Ozone-Induced, Neutrophil-Independent Airway Hyper-Responsiveness in Mice
- (2010) Philip R. Cooper et al. PLoS One
- Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells
- (2010) B. Tchernychev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Both Hematopoietic-Derived and Non–Hematopoietic-Derived β-Arrestin–2 Regulates Murine Allergic Airway Disease
- (2009) John W. Hollingsworth et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
- (2009) X. J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β-Arrestins specifically constrain β2-adrenergic receptor signaling and function in airway smooth muscle
- (2008) Deepak A. Deshpande et al. FASEB JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now