The p38β Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the α-G Helix and MAPK Insert

Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1

(2013) Gian Felice De Nicola et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lipid Molecules Induce p38α Activation via a Novel Molecular Switch

(2012) Netanel Tzarum et al.   JOURNAL OF MOLECULAR BIOLOGY

Design principles underpinning the regulatory diversity of protein kinases

(2012) K. Oruganty et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evolution of the eukaryotic protein kinases as dynamic molecular switches

(2012) S. S. Taylor et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Osmostress Induces Autophosphorylation of Hog1 via a C-Terminal Regulatory Region That Is Conserved in p38α

(2012) Inbal Maayan et al.   PLoS One

DUSPs, to MAP kinases and beyond

(2012) Ching-Yu Huang et al.   Cell and Bioscience

Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation

(2011) L. Jirmanova et al.   BLOOD

Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38α

(2011) Yuan-Yuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

(2011) Min Zheng et al.   NATURE CELL BIOLOGY

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

The three-dimensional structure of MAP kinase p38β: different features of the ATP-binding site in p38β compared with p38α

(2009) Sangita B. Patel et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

p38α Is Active in Vitro and in Vivo When Monophosphorylated at Threonine 180†

(2009) Nadav Askari et al.   BIOCHEMISTRY

The Ste5 Scaffold Directs Mating Signaling by Catalytically Unlocking the Fus3 MAP Kinase for Activation

(2009) Matthew Good et al.   CELL

p38α and p38γ Mediate Oncogenicras-induced Senescence through Differential Mechanisms

(2009) Jinny Kwong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase Activation Loop Autophosphorylation in Cis: Overcoming a Catch-22 Situation

(2009) P. A. Lochhead   Science Signaling

When expressed in yeast, mammalian mitogen-activated protein kinases lose proper regulation and become spontaneously phosphorylated

(2008) Vered Levin-Salomon et al.   BIOCHEMICAL JOURNAL

Genetic disruption of p38  Tyr323 phosphorylation prevents T-cell receptor-mediated p38  activation and impairs interferon-  production

(2008) L. Jirmanova et al.   BLOOD

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

(2008) Ashley C W Pike et al.   EMBO JOURNAL

Enzymatic Activity and Substrate Specificity of Mitogen-activated Protein Kinase p38α in Different Phosphorylation States

(2008) Yuan-Yuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of Intrinsically Active (MEK-independent) Variants of the ERK Family of Mitogen-activated Protein (MAP) Kinases

(2008) Vered Levin-Salomon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen-Exchange Mass Spectrometry Reveals Activation-Induced Changes in the Conformational Mobility of p38α MAP Kinase

(2008) Kevin M. Sours et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification and Characterization of a General Nuclear Translocation Signal in Signaling Proteins

(2008) Dana Chuderland et al.   MOLECULAR CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

A helix scaffold for the assembly of active protein kinases

(2008) A. P. Kornev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA