Glucose Activates TORC2-Gad8 Protein via Positive Regulation of the cAMP/cAMP-dependent Protein Kinase A (PKA) Pathway and Negative Regulation of the Pmk1 Protein-Mitogen-activated Protein Kinase Pathway

Rho1 GTPase and PKC Ortholog Pck1 Are Upstream Activators of the Cell Integrity MAPK Pathway in Fission Yeast

(2014) Laura Sánchez-Mir et al.   PLoS One

TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast

(2013) Charalampos Rallis et al.   AGING CELL

Role of the fission yeast cell integrity MAPK pathway in response to glucose limitation

(2013) Marisa Madrid et al.   BMC MICROBIOLOGY

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

(2013) Sean J. Humphrey et al.   Cell Metabolism

Autoregulation of the Mechanistic Target of Rapamycin (mTOR) Complex 2 Integrity Is Controlled by an ATP-dependent Mechanism

(2013) Chien-Hung Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TORC2 Is Required to Maintain Genome Stability during S Phase in Fission Yeast

(2013) Miriam Schonbrun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of the TOR ATP binding domain by AGC kinase constitutes a novel mode of TOR inhibition

(2013) Lenka Hálová et al.   JOURNAL OF CELL BIOLOGY

Isp7 Is a Novel Regulator of Amino Acid Uptake in the TOR Signaling Pathway

(2013) Dana Laor et al.   MOLECULAR AND CELLULAR BIOLOGY

TORC2 Signaling Pathway Guarantees Genome Stability in the Face of DNA Strand Breaks

(2013) Kenji Shimada et al.   MOLECULAR CELL

Crosstalk between mTOR complexes

(2013) Jianling Xie et al.   NATURE CELL BIOLOGY

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

(2013) Pengda Liu et al.   NATURE CELL BIOLOGY

Amino acid signalling upstream of mTOR

(2013) Jenna L. Jewell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

(2012) Stacey Robida-Stubbs et al.   Cell Metabolism

TORC1 of fission yeast is rapamycin-sensitive

(2012) Terunao Takahara et al.   GENES TO CELLS

The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast

(2012) N. Valbuena et al.   JOURNAL OF CELL SCIENCE

AMPK phosphorylation by Ssp1 is required for proper sexual differentiation in fission yeast

(2012) N. Valbuena et al.   JOURNAL OF CELL SCIENCE

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

A brief history of TOR: Table 1

(2011) Robbie Loewith   BIOCHEMICAL SOCIETY TRANSACTIONS

Snf1-Like Protein Kinase Ssp2 Regulates Glucose Derepression in Schizosaccharomyces pombe

(2011) Tomohiko Matsuzawa et al.   EUKARYOTIC CELL

Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases

(2011) M. Yanagida et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe

(2011) N. Ikai et al.   Open Biology

Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control

(2010) Kyoko Ikeda et al.   CELL CYCLE

Rab-Family GTPase Regulates TOR Complex 2 Signaling in Fission Yeast

(2010) Hisashi Tatebe et al.   CURRENT BIOLOGY

Glucose Signaling-Mediated Coordination of Cell Growth and Cell Cycle in Saccharomyces Cerevisiae

(2010) Stefano Busti et al.   SENSORS

Global fitness profiling of fission yeast deletion strains by barcode sequencing

(2010) Tian Xu Han et al.   GENOME BIOLOGY

TOR Complex 2 Controls Gene Silencing, Telomere Length Maintenance, and Survival under DNA-Damaging Conditions

(2009) M. Schonbrun et al.   MOLECULAR AND CELLULAR BIOLOGY

TOR complex 2: a signaling pathway of its own

(2009) Nadine Cybulski et al.   TRENDS IN BIOCHEMICAL SCIENCES

Activation of the cell integrity pathway is channelled through diverse signalling elements in fission yeast

(2008) Gregorio Barba et al.   CELLULAR SIGNALLING

Syndecan-4 Regulates Subcellular Localization of mTOR Complex2 and Akt Activation in a PKCα-Dependent Manner in Endothelial Cells

(2008) Chohreh Partovian et al.   MOLECULAR CELL

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE