Ovarian Cancer Cell Heparan Sulfate 6-O-Sulfotransferases Regulate an Angiogenic Program Induced by Heparin-binding Epidermal Growth Factor (EGF)-like Growth Factor/EGF Receptor Signaling

An IL6-correlated signature in serous epithelial ovarian cancer associates with growth factor response

(2013) Patrizia Pinciroli et al.   BMC GENOMICS

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

The influence of glycosaminoglycans on IL-8-mediated functions of neutrophils

(2012) Denise Schlorke et al.   CARBOHYDRATE RESEARCH

Endothelial Heparan Sulfate 6-O-Sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor

(2012) Cristina Ferreras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

(2012) Joanna J. Phillips et al.   JOURNAL OF CLINICAL INVESTIGATION

OCEANS: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Chemotherapy With or Without Bevacizumab in Patients With Platinum-Sensitive Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

(2012) Carol Aghajanian et al.   JOURNAL OF CLINICAL ONCOLOGY

Synthesis and Scalable Conversion of l-Iduronamides to Heparin-Related Di- and Tetrasaccharides

(2012) Steen U. Hansen et al.   JOURNAL OF ORGANIC CHEMISTRY

First Gram-Scale Synthesis of a Heparin-Related Dodecasaccharide

(2012) Steen U. Hansen et al.   ORGANIC LETTERS

A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment

(2011) H. Kulbe et al.   CANCER RESEARCH

Characterization of the interaction of interleukin-8 with hyaluronan, chondroitin sulfate, dermatan sulfate and their sulfated derivatives by spectroscopy and molecular modeling

(2011) Annelie Pichert et al.   GLYCOBIOLOGY

Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer

(2011) Robert A. Burger et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Phase 3 Trial of Bevacizumab in Ovarian Cancer

(2011) Timothy J. Perren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting the heparin-binding epidermal growth factor-like growth factor in ovarian cancer therapy

(2010) Hiroshi Tsujioka et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Heparan Sulfate Domain Organization and Sulfation Modulate FGF-induced Cell Signaling

(2010) Nadja Jastrebova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic Heparan Sulfate Oligosaccharides Inhibit Endothelial Cell Functions Essential for Angiogenesis

(2010) Claire L. Cole et al.   PLoS One

Specific inhibition of FGF-2 signaling with 2-O-sulfated octasaccharides of heparan sulfate

(2009) S. Ashikari-Hada et al.   GLYCOBIOLOGY

Scalable Synthesis ofl-Iduronic Acid Derivatives via Stereocontrolled Cyanohydrin Reaction for Synthesis of Heparin-Related Disaccharides

(2009) Steen Uldall Hansen et al.   ORGANIC LETTERS

Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer

(2008) Hiroshi Yagi et al.   INTERNATIONAL JOURNAL OF CANCER

Effect of Interleukin-8 Gene Silencing With Liposome-Encapsulated Small Interfering RNA on Ovarian Cancer Cell Growth

(2008) William M. Merritt et al.   JNCI-Journal of the National Cancer Institute