Lipin 2 Binds Phosphatidic Acid by the Electrostatic Hydrogen Bond Switch Mechanism Independent of Phosphorylation

Assembly of High Molecular Weight Complexes of Lipin on a Supported Lipid Bilayer Observed by Atomic Force Microscopy

(2013) Carl E. Creutz et al.   BIOCHEMISTRY

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

(2013) M. F. Michelle Sim et al.   DIABETOLOGIA

Distinct Roles of the Phosphatidate Phosphatases Lipin 1 and 2 during Adipogenesis and Lipid Droplet Biogenesis in 3T3-L1 Cells

(2013) Hiroshi Sembongi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Lipin 1 and Charge on the Phosphatidic Acid Head Group Control Its Phosphatidic Acid Phosphatase Activity and Membrane Association

(2013) James M. Eaton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling

(2013) Lauren S. Csaki et al.   PROGRESS IN LIPID RESEARCH

Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum

(2012) J. R. Dwyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1

(2012) M.F. Michelle Sim et al.   Molecular Metabolism

Putting the pH into phosphatidic acid signaling

(2011) John JH Shin et al.   BMC BIOLOGY

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance

(2011) D. Ryu et al.   DIABETES

Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis

(2011) Weihua Fei et al.   JOURNAL OF LIPID RESEARCH

Dual function lipin proteins and glycerolipid metabolism

(2011) Thurl E. Harris et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Lipin proteins form homo- and hetero-oligomers

(2010) Guang-Hui Liu et al.   BIOCHEMICAL JOURNAL

Seipin Is a Discrete Homooligomer

(2010) Derk Binns et al.   BIOCHEMISTRY

Characterization of the HumanLPIN1-encoded Phosphatidate Phosphatase Isoforms

(2010) Gil-Soo Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism

(2010) B. P. Young et al.   SCIENCE

Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases

(2009) David N. Brindley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Conserved Serine Residue Is Required for the Phosphatidate Phosphatase Activity but Not the Transcriptional Coactivator Functions of Lipin-1 and Lipin-2

(2009) Jimmy Donkor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipin 2 Is a Liver-enriched Phosphatidate Phosphohydrolase Enzyme That Is Dynamically Regulated by Fasting and Obesity in Mice

(2009) Matthew C. Gropler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-stimulated Interaction with 14-3-3 Promotes Cytoplasmic Localization of Lipin-1 in Adipocytes

(2009) Miklós Péterfy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2

(2008) Neil Grimsey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY