Cytosolic Branched Chain Aminotransferase (BCATc) Regulates mTORC1 Signaling and Glycolytic Metabolism in CD4+T Cells

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

(2013) Madhusudhanan Sukumar et al.   JOURNAL OF CLINICAL INVESTIGATION

Indoleamine 2,3-Dioxygenase Activity Contributes to Local Immune Suppression in the Skin Expressing Human Papillomavirus Oncoprotein E7

(2013) Deepak Mittal et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma

(2013) Wen Zhou et al.   Molecular Cancer

Slc7a5 helps T cells get with the program

(2013) Jonathan D Powell   NATURE IMMUNOLOGY

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

(2013) Linda V Sinclair et al.   NATURE IMMUNOLOGY

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

(2013) Martje Tönjes et al.   NATURE MEDICINE

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Effective T-cell recall responses require the taurine transporter Taut

(2012) Susanne Kaesler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

mTOR, metabolism, and the regulation of T-cell differentiation and function

(2012) Adam T. Waickman et al.   IMMUNOLOGICAL REVIEWS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Expression of mitochondrial branched-chain aminotransferase and α-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism

(2012) Jeffrey T. Cole et al.   Frontiers in Neuroanatomy

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

mTOR upregulation of glycolytic enzymes promotes tumor development

(2011) Xiaojun Zha et al.   CELL CYCLE

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

ConTra v2: a tool to identify transcription factor binding sites across species, update 2011

(2011) Stefan Broos et al.   NUCLEIC ACIDS RESEARCH

mTOR Signaling

(2011) M. Laplante et al.   Cold Spring Harbor Perspectives in Biology

Metabolism in T cell activation and differentiation

(2010) Erika L Pearce   CURRENT OPINION IN IMMUNOLOGY

The metabolic life and times of a T-cell

(2010) Ryan D. Michalek et al.   IMMUNOLOGICAL REVIEWS

Transamination Is Required for α-Ketoisocaproate but Not Leucine to Stimulate Insulin Secretion

(2010) Yingsheng Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation

(2010) E. L. Carr et al.   JOURNAL OF IMMUNOLOGY

Glutamine addiction: a new therapeutic target in cancer

(2010) David R. Wise et al.   TRENDS IN BIOCHEMICAL SCIENCES

Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion

(2009) Akos A. Gerencser et al.   ANALYTICAL CHEMISTRY

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Anergic T Cells Are Metabolically Anergic

(2009) Y. Zheng et al.   JOURNAL OF IMMUNOLOGY

Infectious tolerance via the consumption of essential amino acids and mTOR signaling

(2009) S. P. Cobbold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Advances in measuring cellular bioenergetics using extracellular flux

(2008) David A. Ferrick et al.   DRUG DISCOVERY TODAY

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of arginine metabolism in immunity and immunopathology

(2007) Elisa Peranzoni et al.   IMMUNOBIOLOGY