Synthesis of High Titer Infectious Prions with Cofactor Molecules

Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties

(2013) Enrico Cancellotti et al.   EMBO JOURNAL

Changes in prion replication environment cause prion strain mutation

(2013) Nuria Gonzalez-Montalban et al.   FASEB JOURNAL

De novo generation of infectious prions with bacterially expressed recombinant prion protein

(2013) Zhihong Zhang et al.   FASEB JOURNAL

Recombinant Prion Protein Refolded with Lipid and RNA Has the Biochemical Hallmarks of a Prion but Lacks In Vivo Infectivity

(2013) Andrew G. Timmes et al.   PLoS One

Stabilization of a Prion Strain of Synthetic Origin Requires Multiple Serial Passages

(2012) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New Mechanism for Transmissible Prion Diseases

(2012) N. Makarava et al.   JOURNAL OF NEUROSCIENCE

Strain-Specific Role of RNAs in Prion Replication

(2012) P. Saa et al.   JOURNAL OF VIROLOGY

Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids

(2012) N. R. Deleault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions

(2012) N. R. Deleault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seeding Specificity and Ultrastructural Characteristics of Infectious Recombinant Prions

(2011) Justin R. Piro et al.   BIOCHEMISTRY

Genesis of Mammalian Prions: From Non-infectious Amyloid Fibrils to a Transmissible Prion Disease

(2011) Natallia Makarava et al.   PLoS Pathogens

Ultra-Efficient PrPSc Amplification Highlights Potentialities and Pitfalls of PMCA Technology

(2011) Gian Mario Cosseddu et al.   PLoS Pathogens

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

(2010) Natallia Makarava et al.   ACTA NEUROPATHOLOGICA

Species-Dependent Differences in Cofactor Utilization for Formation of the Protease-Resistant Prion Protein in Vitro

(2010) Nathan R. Deleault et al.   BIOCHEMISTRY

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

(2010) Jae-Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

Protease-Sensitive Synthetic Prions

(2010) David W. Colby et al.   PLoS Pathogens

Prion Protein Glycosylation Is Not Required for Strain-Specific Neurotropism

(2009) J. R. Piro et al.   JOURNAL OF VIROLOGY

Cell-free propagation of prion strains

(2008) Joaquín Castilla et al.   EMBO JOURNAL