Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments

(2014) Meena Choi et al.   BIOINFORMATICS

Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

(2012) James P. Clement et al.   CELL

Mutations inSYNGAP1Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency

(2012) Martin H. Berryer et al.   HUMAN MUTATION

Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics

(2012) Amelia C. Peterson et al.   MOLECULAR & CELLULAR PROTEOMICS

Cyclin-Dependent Kinases in Brain Development and Disease

(2011) Susan C. Su et al.   Annual Review of Cell and Developmental Biology

De Novo SYNGAP1 Mutations in Nonsyndromic Intellectual Disability and Autism

(2011) Fadi F. Hamdan et al.   BIOLOGICAL PSYCHIATRY

Deletion of Densin-180 Results in Abnormal Behaviors Associated with Mental Illness and Reduces mGluR5 and DISC1 in the Postsynaptic Density Fraction

(2011) H. J. Carlisle et al.   JOURNAL OF NEUROSCIENCE

Effect of mass spectrometric parameters on peptide and protein identification rates for shotgun proteomic experiments on an LTQ-orbitrap mass analyzer

(2011) Anastasia Kalli et al.   PROTEOMICS

Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function

(2011) G. Turrigiano   Cold Spring Harbor Perspectives in Biology

Effect of High-Accuracy Precursor Masses on Phosphopeptide Identification from MS3Spectra

(2010) Wiebke Timm et al.   ANALYTICAL CHEMISTRY

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Confident Phosphorylation Site Localization Using the Mascot Delta Score

(2010) Mikhail M. Savitski et al.   MOLECULAR & CELLULAR PROTEOMICS

Epac2-mediated dendritic spine remodeling: Implications for disease

(2010) Peter Penzes et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

CaMKII Triggers the Diffusional Trapping of Surface AMPARs through Phosphorylation of Stargazin

(2010) Patricio Opazo et al.   NEURON

RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2-specific nucleotide exchange

(2009) Elif Yaman et al.   FEBS Journal

AMPA Receptor Incorporation into Synapses during LTP: The Role of Lateral Movement and Exocytosis

(2009) Hiroshi Makino et al.   NEURON

Mutations inSYNGAP1in Autosomal Nonsyndromic Mental Retardation

(2009) Fadi F. Hamdan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolving Cell Signals

(2009) M. O. Collins   SCIENCE

Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

(2009) L. J. Holt et al.   SCIENCE

The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

(2008) Vladimir Pena et al.   EMBO REPORTS

SynGAP Regulates Steady-State and Activity-Dependent Phosphorylation of Cofilin

(2008) H. J. Carlisle et al.   JOURNAL OF NEUROSCIENCE

Critical Role of CDK5 and Polo-like Kinase 2 in Homeostatic Synaptic Plasticity during Elevated Activity

(2008) Daniel P. Seeburg et al.   NEURON

Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts

(2007) Heath E. Klock et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS