Nicotinamide Nucleotide Transhydrogenase (Nnt) Links the Substrate Requirement in Brain Mitochondria for Hydrogen Peroxide Removal to the Thioredoxin/Peroxiredoxin (Trx/Prx) System

A novel homozygous mutation of the nicotinamide nucleotide transhydrogenase gene in a Japanese patient with familial glucocorticoid deficiency

(2013) Rie Yamaguchi et al.   ENDOCRINE JOURNAL

A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

(2013) Juliana A. Ronchi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity

(2013) John T. Heiker et al.   Obesity

Why do bacteria use so many enzymes to scavenge hydrogen peroxide?

(2012) Surabhi Mishra et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Calcium, Bioenergetics, and Neuronal Vulnerability in Parkinson's Disease

(2012) D. James Surmeier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria and cell signalling

(2012) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency

(2012) Eirini Meimaridou et al.   NATURE GENETICS

Thioredoxin Reductase Deficiency Potentiates Oxidative Stress, Mitochondrial Dysfunction and Cell Death in Dopaminergic Cells

(2012) Pamela Lopert et al.   PLoS One

Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases

(2011) Tohru Fukai et al.   ANTIOXIDANTS & REDOX SIGNALING

Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells

(2011) Fei Yin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H2O2

(2011) David Cantu et al.   JOURNAL OF NEUROCHEMISTRY

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium

(2010) Freya L. Sheeran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Respiration-dependent H2O2Removal in Brain Mitochondria via the Thioredoxin/Peroxiredoxin System

(2010) Derek A. Drechsel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic modifier of mitochondrial superoxide dismutase-deficient mice delays heart failure and prolongs survival

(2010) Aekyong Kim et al.   MAMMALIAN GENOME

The energy–redox axis in aging and age-related neurodegeneration☆

(2009) Li-Peng Yap et al.   ADVANCED DRUG DELIVERY REVIEWS

The Deletion Variant of Nicotinamide Nucleotide Transhydrogenase (Nnt) Does Not Affect Insulin Secretion or Glucose Tolerance

(2009) Nicole Wong et al.   ENDOCRINOLOGY

Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production

(2009) Philip Y. Lam et al.   FREE RADICAL RESEARCH

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Aging Brain

(2008) Bruce A. Yankner et al.   Annual Review of Pathology-Mechanisms of Disease

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Isolation of mitochondria from rat brain using Percoll density gradient centrifugation

(2008) Neil R Sims et al.   Nature Protocols

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING