β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 17, Pages 12052-12062
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-03-12
DOI
10.1074/jbc.m113.525212
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Age-Related Oxidative Modifications of Transthyretin Modulate Its Amyloidogenicity
- (2013) Lei Zhao et al. BIOCHEMISTRY
- Oxidation and ubiquitination in neurodegeneration
- (2013) Beat M Riederer et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance
- (2013) Itender Singh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein Carbonylation and Aggregation Precede Neuronal Apoptosis Induced by Partial Glutathione Depletion
- (2012) Anushka Dasgupta et al. ASN Neuro
- Metal dyshomeostasis and oxidative stress in Alzheimer’s disease
- (2012) Mark A. Greenough et al. NEUROCHEMISTRY INTERNATIONAL
- Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+on Amyloid-β Stability, Oligomerization, and Aggregation
- (2011) Wei-Ting Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics
- (2010) James A. Duce et al. PROGRESS IN NEUROBIOLOGY
- Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution
- (2010) Harry Levine PROTEIN SCIENCE
- RNA oxidation in Alzheimer disease and related neurodegenerative disorders
- (2009) Akihiko Nunomura et al. ACTA NEUROPATHOLOGICA
- Overcoming synthetic Aβ peptide aging: a new approach to an age-old problem
- (2009) Claudia Manzoni et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Aβ-mediated ROS production by Cu ions: Structural insights, mechanisms and relevance to Alzheimer's disease
- (2009) Christelle Hureau et al. BIOCHIMIE
- Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-β (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators
- (2009) Vello Tõugu et al. JOURNAL OF NEUROCHEMISTRY
- Mechanism of Hydrogen Peroxide Production by Copper-Bound Amyloid Beta Peptide: A Theoretical Study
- (2009) Nadine Hewitt et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction
- (2009) Jennifer L. Tomic et al. NEUROBIOLOGY OF DISEASE
- Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease
- (2008) David Allsop et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Influence of Multiple Metal Ions on β-Amyloid Aggregation and Dissociation on a Solid Surface†
- (2008) Jungki Ryu et al. BIOCHEMISTRY
- Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide
- (2008) Peter Faller et al. DALTON TRANSACTIONS
- Binding of zinc(II) and copper(II) to the full-length Alzheimer’s amyloid-β peptide
- (2007) Vello Tõugu et al. JOURNAL OF NEUROCHEMISTRY
- Characterization of Copper Interactions with Alzheimer Amyloid β Peptides
- (2003) Craig S. Atwood et al. JOURNAL OF NEUROCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search