α-Actinin 4 Potentiates Nuclear Factor κ-Light-chain-enhancer of Activated B-cell (NF-κB) Activity in Podocytes Independent of Its Cytoplasmic Actin Binding Function

Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.

(2015) Vasilisa Aksenova et al.   Oncotarget

Role of Transcription Factor Acetylation in Diabetic Kidney Disease

(2014) R. Liu et al.   DIABETES

Close Relations between Podocyte Injuries and Membranous Proliferative Glomerulonephritis in Autoimmune Murine Models

(2013) Junpei Kimura et al.   AMERICAN JOURNAL OF NEPHROLOGY

β-Transducin Repeat-containing Protein 1 (β-TrCP1)-mediated Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor (SMRT) Protein Degradation Promotes Tumor Necrosis Factor α (TNFα)-induced Inflammatory Gene Expression

(2013) Kuo-Sheng Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Leucine Zipper Protein (sLZIP) Negatively Regulates Skeletal Muscle Differentiation via Interaction with α-Actinin-4

(2013) Hyoung-Tae An et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of Podocyte Injuries in Osborne–Mendel Rats is Accompanied by Reduced Expression of Podocyte Proteins

(2013) K. Yasuno et al.   JOURNAL OF COMPARATIVE PATHOLOGY

c-mip Down-Regulates NF-κB Activity and Promotes Apoptosis in Podocytes

(2012) Virginie Ory et al.   AMERICAN JOURNAL OF PATHOLOGY

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Identification of a Novel LXXLL Motif in α-Actinin 4-spliced Isoform That Is Critical for Its Interaction with Estrogen Receptor α and Co-activators

(2012) Simran Khurana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial Focal Segmental Glomerulosclerosis (FSGS)-linked α-Actinin 4 (ACTN4) Protein Mutants Lose Ability to Activate Transcription by Nuclear Hormone Receptors

(2012) Simran Khurana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiviral Innate Immunity Disturbs Podocyte Cell Function

(2012) Michifumi Yamashita et al.   Journal of Innate Immunity

Genetic causes of focal segmental glomerulosclerosis: implications for clinical practice

(2012) I. M. Rood et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

New players in the pathogenesis of focal segmental glomerulosclerosis

(2012) C. Schell et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein

(2012) D Guan et al.   ONCOGENE

The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation

(2012) Laura Tornatore et al.   TRENDS IN CELL BIOLOGY

α-Actinin-4 and CLP36 Protein Deficiencies Contribute to Podocyte Defects in Multiple Human Glomerulopathies

(2011) Zhongmin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α

(2011) Leslie A Bruggeman et al.   LABORATORY INVESTIGATION

Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF- B and silenced by DNA methylation

(2011) M. Ristola et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Actin-binding Protein, Actinin Alpha 4 (ACTN4), Is a Nuclear Receptor Coactivator that Promotes Proliferation of MCF-7 Breast Cancer Cells

(2010) Simran Khurana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB addiction and its role in cancer: ‘one size does not fit all’

(2010) M M Chaturvedi et al.   ONCOGENE

Nephrin Deficiency Activates NF- B and Promotes Glomerular Injury

(2009) S. Hussain et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis

(2009) S. Dai et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

ACTN4 Gene Mutations and Single Nucleotide Polymorphisms in Idiopathic Focal Segmental Glomerulosclerosis

(2009) Shengchuan Dai et al.   NEPHRON CLINICAL PRACTICE

Familial Focal Segmental Glomerulosclerosis Associated With an ACTN4 Mutation and Paternal Germline Mosaicism

(2008) Hyun Jin Choi et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Expression of Alpha-actinin-4 in Human Diabetic Nephropathy

(2008) Moritsugu Kimura et al.   INTERNAL MEDICINE

RelA/NF-κB transcription factor associates with α-actinin-4

(2007) Vladimir N. Babakov et al.   EXPERIMENTAL CELL RESEARCH