Absent, Small or Homeotic 2-like Protein (ASH2L) Enhances the Transcription of the Estrogen Receptor α Gene through GATA-binding Protein 3 (GATA3)

ZNF703is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

(2011) Daniel G. Holland et al.   EMBO Molecular Medicine

Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

(2011) Yun-Yong Park et al.   EMBO Molecular Medicine

ZNF703gene amplification at 8p12 specifies luminal B breast cancer

(2011) Fabrice Sircoulomb et al.   EMBO Molecular Medicine

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding

(2011) Yong Chen et al.   EMBO REPORTS

Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain

(2011) Sabina Sarvan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ash2l interacts with Tbx1 and is required during early embryogenesis

(2010) Jason Z Stoller et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing

(2010) Khairul I. Ansari et al.   FEBS Journal

From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation

(2010) Tomonori Hosoya et al.   IMMUNOLOGICAL REVIEWS

A Novel Non-SET Domain Multi-subunit Methyltransferase Required for Sequential Nucleosomal Histone H3 Methylation by the Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2010) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

(2010) Fang Cao et al.   PLoS One

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

(2009) Jeremy M. Arnold et al.   BREAST CANCER RESEARCH AND TREATMENT

Identification and Characterization of a Novel Nuclear Protein Complex Involved in Nuclear Hormone Receptor-mediated Gene Regulation

(2009) Shivani Garapaty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Human Trithorax Protein hASH2 Functions as an Oncoprotein

(2008) J. Luscher-Firzlaff et al.   CANCER RESEARCH

GATA-3 and the regulation of the mammary luminal cell fate

(2008) Hosein Kouros-Mehr et al.   CURRENT OPINION IN CELL BIOLOGY

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

GATA-3 as a Marker of Hormone Response in Breast Cancer

(2008) Sandy H. Fang et al.   JOURNAL OF SURGICAL RESEARCH

Role of the GATA Family of Transcription Factors in Endocrine Development, Function, and Disease

(2008) Robert S. Viger et al.   MOLECULAR ENDOCRINOLOGY

Transcription factor Ap2  associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription

(2008) C. C. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA