Identification of a Face Enhancer Reveals Direct Regulation of LIM Homeobox 8 (Lhx8) by Wingless-Int (WNT)/β-Catenin Signaling

TGF  regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate

(2014) J.-i. Iwata et al.   DEVELOPMENT

Inhibition of Wnt/β-catenin pathway by Dikkopf-1 affects midfacial morphogenesis in chick embryo

(2014) Masayoshi Kawakami et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

A High-Resolution Enhancer Atlas of the Developing Telencephalon

(2013) Axel Visel et al.   CELL

The Evolution of Lineage-Specific Regulatory Activities in the Human Embryonic Limb

(2013) Justin Cotney et al.   CELL

A homozygous 237-kb deletion at 1p31 identified as the locus for midline cleft of the upper and lower lip in a consanguineous family

(2013) Yeşerin Yıldırım et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Insights into neural crest development and evolution from genomic analysis

(2013) M. Simoes-Costa et al.   GENOME RESEARCH

A Network of Transcription Factors Operates during Early Tooth Morphogenesis

(2013) Minglian Zhao et al.   MOLECULAR AND CELLULAR BIOLOGY

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers

(2013) C. Attanasio et al.   SCIENCE

A Critical Role for PDGFRα Signaling in Medial Nasal Process Development

(2013) Fenglei He et al.   PLoS Genetics

Critical selection of internal control genes for quantitative real-time RT-PCR studies in lipopolysaccharide-stimulated human THP-1 and K562 cells

(2012) Xi-mei Cao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigenomic Annotation of Enhancers Predicts Transcriptional Regulators of Human Neural Crest

(2012) Alvaro Rada-Iglesias et al.   Cell Stem Cell

Current perspectives of the signaling pathways directing neural crest induction

(2012) Timothy J. Stuhlmiller et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The neural crest in vertebrate evolution

(2012) Nicole M Le Douarin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Wnt9b-dependent FGF signaling is crucial for outgrowth of the nasal and maxillary processes during upper jaw and lip development

(2012) Y.-R. Jin et al.   DEVELOPMENT

New perspectives on pharyngeal dorsoventral patterning in development and evolution of the vertebrate jaw

(2012) Daniel Meulemans Medeiros et al.   DEVELOPMENTAL BIOLOGY

Cleft palate defect ofDlx1/2−/− mutant mice is caused by lack of vertical outgrowth in the posterior palate

(2012) Juhee Jeong et al.   DEVELOPMENTAL DYNAMICS

Asymmetric requirement of surface epithelial β-catenin during the upper and lower jaw development

(2012) Ye Sun et al.   DEVELOPMENTAL DYNAMICS

Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb

(2012) Justin Cotney et al.   GENOME RESEARCH

The LIM Homeodomain Transcription Factor LHX6

(2012) Zichao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A map of the cis-regulatory sequences in the mouse genome

(2012) Yin Shen et al.   NATURE

Transcriptional enhancers in development and disease

(2012) Noboru Sakabe et al.   GENOME BIOLOGY

Variation in FGF1, FOXE1, and TIMP2genes is associated with nonsyndromic cleft lip with or without cleft palate

(2011) Tiit Nikopensius et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Genetics of Nonsyndromic Orofacial Clefts

(2011) Fedik Rahimov et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Enhancers: From Developmental Genetics to the Genetics of Common Human Disease

(2011) Iain Williamson et al.   DEVELOPMENTAL CELL

A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis

(2011) Elisabetta Ferretti et al.   DEVELOPMENTAL CELL

Fibroblast Growth Factor 9 (FGF9)-Pituitary Homeobox 2 (PITX2) Pathway Mediates Transforming Growth Factor β (TGFβ) Signaling to Regulate Cell Proliferation in Palatal Mesenchyme during Mouse Palatogenesis

(2011) Jun-ichi Iwata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Large-scale discovery of enhancers from human heart tissue

(2011) Dalit May et al.   NATURE GENETICS

Cranial neural crest cells on the move: Their roles in craniofacial development

(2010) Dwight R. Cordero et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Genomics of Long-Range Regulatory Elements

(2010) James P. Noonan et al.   Annual Review of Genomics and Human Genetics

Molecular mechanisms of cranial neural crest cell migration and patterning in craniofacial development

(2010) M. Minoux et al.   DEVELOPMENT

Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4

(2010) Sayumi Fujimori et al.   DEVELOPMENTAL BIOLOGY

Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression

(2010) Fenglei He et al.   DEVELOPMENTAL BIOLOGY

The canonical Wnt/ß-catenin signaling pathway regulates Fgf signaling for early facial development

(2010) Yongping Wang et al.   DEVELOPMENTAL BIOLOGY

Ectodermal WNT/β-catenin signaling shapes the mouse face

(2010) Bethany S. Reid et al.   DEVELOPMENTAL BIOLOGY

Wnt/β-catenin Signaling in Oral Tissue Development and Disease

(2010) F. Liu et al.   JOURNAL OF DENTAL RESEARCH

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

ChIP-Seq identification of weakly conserved heart enhancers

(2010) Matthew J Blow et al.   NATURE GENETICS

The mouse Gene Expression Database (GXD): 2011 update

(2010) J. H. Finger et al.   NUCLEIC ACIDS RESEARCH

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets

(2009) J. W. Nicol et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion

(2009) L. Song et al.   DEVELOPMENT

The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition

(2009) Myrto Denaxa et al.   DEVELOPMENTAL BIOLOGY

Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development

(2009) Jianquan Chen et al.   DEVELOPMENTAL BIOLOGY

New directions in craniofacial morphogenesis

(2009) Heather L. Szabo-Rogers et al.   DEVELOPMENTAL BIOLOGY

Transforming Growth Factor-β Regulates Basal Transcriptional Regulatory Machinery to Control Cell Proliferation and Differentiation in Cranial Neural Crest-derived Osteoprogenitor Cells

(2009) Jun-ichi Iwata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unraveling Human Cleft Lip and Palate Research

(2009) A.R. Vieira   JOURNAL OF DENTAL RESEARCH

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Genomic views of distant-acting enhancers

(2009) Axel Visel et al.   NATURE

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Ultraconservation identifies a small subset of extremely constrained developmental enhancers

(2008) Axel Visel et al.   NATURE GENETICS

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis

(2007) Fei Liu et al.   DEVELOPMENTAL BIOLOGY