Dopamine D2 Receptor Relies upon PPM/PP2C Protein Phosphatases to Dephosphorylate Huntingtin Protein

Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site

(2013) Chang Pan et al.   Scientific Reports

The human phosphatase interactome: An intricate family portrait

(2012) Francesca Sacco et al.   FEBS LETTERS

Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation

(2011) L. S. Havel et al.   HUMAN MOLECULAR GENETICS

Kinase inhibitors modulate huntingtin cell localization and toxicity

(2011) Randy Singh Atwal et al.   Nature Chemical Biology

FK506 ameliorates cell death features in Huntington’s disease striatal cell models

(2011) Tatiana R. Rosenstock et al.   NEUROCHEMISTRY INTERNATIONAL

Phosphorylation of Huntingtin at Ser421 in YAC128 Neurons Is Associated with Protection of YAC128 Neurons from NMDA-Mediated Excitotoxicity and Is Modulated by PP1 and PP2A

(2010) M. Metzler et al.   JOURNAL OF NEUROSCIENCE

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Phosphorylation of Threonine 3

(2009) Charity T. Aiken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

(2009) Xiaofeng Gu et al.   NEURON

Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease

(2009) Jose R Pineda et al.   Molecular Brain

PPM1A and PPM1B act as IKKβ phosphatases to terminate TNFα-induced IKKβ-NF-κB activation

(2008) W SUN et al.   CELLULAR SIGNALLING

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

(2008) Emilie Colin et al.   EMBO JOURNAL

Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo

(2007) Delphine Charvin et al.   NEUROBIOLOGY OF DISEASE