Phosphorylation of the Transcription Activator CLOCK Regulates Progression through a ∼24-h Feedback Loop to Influence the Circadian Period inDrosophila

The CK2 Kinase Stabilizes CLOCK and Represses Its Activity in the Drosophila Circadian Oscillator

(2013) Áron Szabó et al.   PLOS BIOLOGY

Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila

(2013) David S. Garbe et al.   PLoS Genetics

CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila

(2012) W. Luo et al.   GENES & DEVELOPMENT

A role for O-GlcNAcylation in setting circadian clock speed

(2012) E. Y. Kim et al.   GENES & DEVELOPMENT

NEMO/NLK Phosphorylates PERIOD to Initiate a Time-Delay Phosphorylation Circuit that Sets Circadian Clock Speed

(2011) Joanna C. Chiu et al.   CELL

A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation

(2011) Mary L. Spengler et al.   CELL CYCLE

NEMO Kinase Contributes to Core Period Determination by Slowing the Pace of the Drosophila Circadian Oscillator

(2011) Wangjie Yu et al.   CURRENT BIOLOGY

Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA

(2010) J. S. Menet et al.   GENES & DEVELOPMENT

A Hierarchical Phosphorylation Cascade That Regulates the Timing of PERIOD Nuclear Entry Reveals Novel Roles for Proline-Directed Kinases and GSK-3 /SGG in Circadian Clocks

(2010) H. W. Ko et al.   JOURNAL OF NEUROSCIENCE

Sequential and Compartment-specific Phosphorylation Controls the Life Cycle of the Circadian CLOCK Protein

(2009) Hsiu-Cheng Hung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DOUBLETIME Plays a Noncatalytic Role To Mediate CLOCK Phosphorylation and Repress CLOCK-Dependent Transcription within the Drosophila Circadian Clock

(2009) W. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Roles of CLOCK Phosphorylation in Suppression of E-Box-Dependent Transcription

(2009) H. Yoshitane et al.   MOLECULAR AND CELLULAR BIOLOGY

Involvement of the Protein Kinase CK2 in the Regulation of Mammalian Circadian Rhythms

(2009) Y. Tsuchiya et al.   Science Signaling

CLOCK expression identifies developing circadian oscillator neurons in the brains of Drosophila embryos

(2008) Jerry H Houl et al.   BMC NEUROSCIENCE

The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock

(2008) J. C. Chiu et al.   GENES & DEVELOPMENT

Activating PER Repressor through a DBT-Directed Phosphorylation Switch

(2008) Saul Kivimäe et al.   PLOS BIOLOGY

Circadian Transcription Contributes to Core Period Determination in Drosophila

(2008) Sebastian Kadener et al.   PLOS BIOLOGY