Structure of theAcinetobacter baumanniiDithiol Oxidase DsbA Bound to Elongation Factor EF-Tu Reveals a Novel Protein Interaction Site

Targeting virulence not viability in the search for future antibacterials

(2015) Begoña Heras et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors

(2014) Róisín M. McMahon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

First Steps Towards a Vaccine against Acinetobacter baumannii

(2014) Meritxell Garcia-Quintanilla et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

New Insights into Dissemination and Variation of the Health Care-Associated Pathogen Acinetobacter baumannii from Genomic Analysis

(2014) M. S. Wright et al.   mBio

Rv2969c, essential for optimal growth inMycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases

(2013) Lakshmanane Premkumar et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Disruption of Biofilm Formation by the Human Pathogen Acinetobacter baumannii Using Engineered Quorum-Quenching Lactonases

(2013) Jeng Yeong Chow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo

(2013) Philip M. Ireland et al.   ANTIOXIDANTS & REDOX SIGNALING

Deciphering the genetic basis ofMoraxella catarrhaliscomplement resistance: a critical role for the disulphide bond formation system

(2013) Stefan P. W. de Vries et al.   MOLECULAR MICROBIOLOGY

Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

(2013) Fabian Kurth et al.   PLoS One

Lysine Trimethylation of EF-Tu Mimics Platelet-Activating Factor To Initiate Pseudomonas aeruginosa Pneumonia

(2013) M. Barbier et al.   mBio

Quality control of disulfide bond formation in pilus subunits by the chaperone FimC

(2012) Maria D Crespo et al.   Nature Chemical Biology

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus

(2012) J. A. Garnett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association ofAcinetobacter baumanniiEF-Tu with Cell Surface, Outer Membrane Vesicles, and Fibronectin

(2012) Shatha F. Dallo et al.   TheScientificWorldJOURNAL

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and Function of DsbA, a Key Bacterial Oxidative Folding Catalyst

(2011) Stephen R. Shouldice et al.   ANTIOXIDANTS & REDOX SIGNALING

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Control of an Outbreak of Carbapenem-Resistant Acinetobacter baumannii in Australia after Introduction of Environmental Cleaning with a Commercial Oxidizing Disinfectant

(2010) Michelle Doidge et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Structural and Functional Characterization of Three DsbA Paralogues fromSalmonella entericaSerovar Typhimurium

(2010) Begoña Heras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Immunospecific Responses to Bacterial Elongation Factor Tu during Burkholderia Infection and Immunization

(2010) Wildaliz Nieves et al.   PLoS One

Structure of the Q  replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins

(2010) R. T. Kidmose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial translation elongation factor EF-Tu interacts and colocalizes with actin-like MreB protein

(2010) H. J. Defeu Soufo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural and Functional Characterization of the Oxidoreductase α-DsbA1 from Wolbachia pipientis

(2009) Mareike Kurz et al.   ANTIOXIDANTS & REDOX SIGNALING

Characterization of the DsbA Oxidative Folding Catalyst from Pseudomonas aeruginosa Reveals a Highly Oxidizing Protein that Binds Small Molecules

(2009) Stephen R. Shouldice et al.   ANTIOXIDANTS & REDOX SIGNALING

Structural and Biochemical Characterization ofXylella fastidiosaDsbA Family Members: New Insights into the Enzyme−Substrate Interaction†‡

(2009) Fábio C. Rinaldi et al.   BIOCHEMISTRY

Regulation ofAcinetobacter baumanniibiofilm formation

(2009) Jennifer A Gaddy et al.   Future Microbiology

Characterization of Two Homologous Disulfide Bond Systems Involved in Virulence Factor Biogenesis in Uropathogenic Escherichia coli CFT073

(2009) M. Totsika et al.   JOURNAL OF BACTERIOLOGY

The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes

(2009) Jason J. Paxman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Function of the Oxidoreductase DsbA1 from Neisseria meningitidis

(2009) Julian P. Vivian et al.   JOURNAL OF MOLECULAR BIOLOGY

DSB proteins and bacterial pathogenicity

(2009) Begoña Heras et al.   NATURE REVIEWS MICROBIOLOGY

TOPCONS: consensus prediction of membrane protein topology

(2009) A. Bernsel et al.   NUCLEIC ACIDS RESEARCH

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

(2009) E. Villa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Disulfide-Containing Chemical Cross-Links in Proteins Using MALDI-TOF/TOF-Mass Spectrometry

(2008) Gordon J. King et al.   ANALYTICAL CHEMISTRY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Acinetobacter baumannii:an emerging multidrug-resistant threat

(2008) Thomas D Gootz et al.   Expert Review of Anti-Infective Therapy

The Periplasmic Disulfide Oxidoreductase DsbA Contributes to Haemophilus influenzae Pathogenesis

(2008) C. V. Rosadini et al.   INFECTION AND IMMUNITY

The Surface-Exposed Carboxyl Region of Mycoplasma pneumoniae Elongation Factor Tu Interacts with Fibronectin

(2008) S. Balasubramanian et al.   INFECTION AND IMMUNITY

Capacity of multidrug-resistant clinical isolates of Acinetobacter baumannii to form biofilm and adhere to epithelial cell surfaces

(2007) H.-W. Lee et al.   CLINICAL MICROBIOLOGY AND INFECTION