TRPM2 Channels Protect against Cardiac Ischemia-Reperfusion Injury

The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury

(2013) Barbara A. Miller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Histone 3.3 Participates in a Self-Sustaining Cascade of Apoptosis That Contributes to the Progression of Chronic Obstructive Pulmonary Disease

(2013) Carlos A. Barrero et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

(2013) Molly Plovanich et al.   PLoS One

HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

(2013) Carlos A. Barrero et al.   PLoS One

EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

(2013) Y. Sancak et al.   SCIENCE

MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity

(2013) Nicholas E. Hoffman et al.   Cell Reports

TRPM2 Ca2+ channel regulates energy balance and glucose metabolism

(2012) Zhiyou Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

TRPM4 channels in the cardiovascular system: Physiology, pathophysiology, and pharmacology

(2012) Hugues Abriel et al.   BIOCHEMICAL PHARMACOLOGY

Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury

(2012) Toshihito Hiroi et al.   CARDIOVASCULAR RESEARCH

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

(2012) Karthik Mallilankaraman et al.   CELL

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism

(2012) Karthik Mallilankaraman et al.   NATURE CELL BIOLOGY

MS Data Miner: A web-based software tool to analyze, compare, and share mass spectrometry protein identifications

(2012) Thomas F. Dyrlund et al.   PROTEOMICS

Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density

(2011) Xue Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger

(2011) Jianliang Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta synthase-deficient mice

(2011) Z. Cheng et al.   BLOOD

Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle

(2011) Christophe Simard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Roles of TRPM2 in oxidative stress

(2011) Nobuaki Takahashi et al.   CELL CALCIUM

Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

(2011) Daniel Tello et al.   Cell Metabolism

TRPC Channels As Effectors of Cardiac Hypertrophy

(2011) Petra Eder et al.   CIRCULATION RESEARCH

Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis

(2011) K. M. Irrinki et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Regulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange

(2010) JuFang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning

(2010) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice

(2010) Ilka Mathar et al.   JOURNAL OF CLINICAL INVESTIGATION

TRPM2: a multifunctional ion channel for calcium signalling

(2010) Adriana Sumoza-Toledo et al.   JOURNAL OF PHYSIOLOGY-LONDON

MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake

(2010) Fabiana Perocchi et al.   NATURE

Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration

(2009) JuFang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Phospholemman and β-adrenergic stimulation in the heart

(2009) JuFang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+-K+-ATPase

(2008) Jianliang Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRP channel and cardiovascular disease

(2008) Hiroyuki Watanabe et al.   PHARMACOLOGY & THERAPEUTICS

Altered functional properties of a TRPM2 variant in Guamanian ALS and PD

(2008) M. C. Hermosura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary determinants of divergent calcium selectivity of TRPM channels

(2007) Michael Mederos y Schnitzler et al.   FASEB JOURNAL