Urokinase-type Plasminogen Activator Receptor (uPAR) Ligation Induces a Raft-localized Integrin Signaling Switch That Mediates the Hypermotile Phenotype of Fibrotic Fibroblasts
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Urokinase-type Plasminogen Activator Receptor (uPAR) Ligation Induces a Raft-localized Integrin Signaling Switch That Mediates the Hypermotile Phenotype of Fibrotic Fibroblasts
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 18, Pages 12791-12804
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-03-19
DOI
10.1074/jbc.m113.498576
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis
- (2013) Qiang Ding et al. AMERICAN JOURNAL OF PATHOLOGY
- β1integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1
- (2013) Hira Lal Goel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- MMP-9 and uPAR regulated glioma cell migration
- (2013) Krishna Kumar Veeravalli et al. Cell Adhesion & Migration
- Recent Developments in Myofibroblast Biology
- (2012) Boris Hinz et al. AMERICAN JOURNAL OF PATHOLOGY
- Teaching an old dogma new tricks: twenty years of Shc adaptor signalling
- (2012) Melanie K. B. Wills et al. BIOCHEMICAL JOURNAL
- suPAR as a prognostic biomarker in sepsis
- (2012) Katia Donadello et al. BMC Medicine
- Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation
- (2011) David Lagares et al. ARTHRITIS AND RHEUMATISM
- Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
- (2011) Yuejuan Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
- (2011) Changli Wei et al. NATURE MEDICINE
- Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells
- (2011) J. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells
- (2010) Hari Raghu et al. BMC CANCER
- Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts
- (2010) Guo-qiang Cai et al. EXPERIMENTAL CELL RESEARCH
- Antagonistic Anti-urokinase Plasminogen Activator Receptor (uPAR) Antibodies Significantly Inhibit uPAR-mediated Cellular Signaling and Migration
- (2010) Sai Duriseti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thy-1-Integrin αvβ5Interactions Inhibit Lung Fibroblast Contraction-induced Latent Transforming Growth Factor-β1 Activation and Myofibroblast Differentiation
- (2010) Yong Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice
- (2010) Kristy A. Bauman et al. JOURNAL OF CLINICAL INVESTIGATION
- Lipid Rafts As a Membrane-Organizing Principle
- (2010) D. Lingwood et al. SCIENCE
- Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins
- (2009) Sha Zhu et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- The urokinase receptor as an entertainer of signal transduction
- (2009) Silvia D'Alessio Frontiers in Bioscience-Landmark
- The interaction between urokinase receptor and vitronectin in cell adhesion and signalling
- (2008) C MADSEN et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Intact and cleaved uPAR forms: diagnostic and prognostic value in cancer
- (2008) Morten et al. Frontiers in Bioscience-Landmark
- Focal Adhesion Kinase (FAK)-related Non-kinase Inhibits Myofibroblast Differentiation through Differential MAPK Activation in a FAK-dependent Manner
- (2008) Qiang Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started