AMP-activated Protein Kinase α2 and E2F1 Transcription Factor Mediate Doxorubicin-induced Cytotoxicity by Forming a Positive Signal Loop in Mouse Embryonic Fibroblasts and Non-carcinoma Cells

The Dark Side of E2F1: In Transit beyond Apoptosis

(2012) D. Engelmann et al.   CANCER RESEARCH

Resveratrol Attenuates Doxorubicin-Induced Cardiomyocyte Apoptosis in Lymphoma Nude Mice by Heme Oxygenase-1 Induction

(2012) Jun Gu et al.   Cardiovascular Toxicology

Bim, a Proapoptotic Protein, Up-regulated via Transcription Factor E2F1-dependent Mechanism, Functions as a Prosurvival Molecule in Cancer

(2012) Raghu Gogada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of AMP-activated Protein Kinase α (AMPKα) by Doxorubicin Accentuates Genotoxic Stress and Cell Death in Mouse Embryonic Fibroblasts and Cardiomyocytes

(2012) Shaobin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Berberine Inhibits Doxorubicin-Triggered Cardiomyocyte Apoptosis via Attenuating Mitochondrial Dysfunction and Increasing Bcl-2 Expression

(2012) Xiuxiu Lv et al.   PLoS One

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Activation of AMP-Activated Protein Kinase Contributes to Doxorubicin-Induced Cell Death and Apoptosis in Cultured Myocardial H9c2 Cells

(2011) Min-Bin Chen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation

(2010) Masanori Konishi et al.   CARDIOVASCULAR RESEARCH

Inhibition of AMP-activated protein kinase pathway sensitizes human leukemia K562 cells to nontoxic concentration of doxorubicin

(2010) Qun Zhu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

(2010) C Ji et al.   ONCOGENE

Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation

(2010) Amy V. Pointon et al.   PLoS One

Doxorubicin: The Good, the Bad and the Ugly Effect

(2009) Cristina Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway

(2009) Elizabeth D. Brookins Danz et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMPK: Lessons from transgenic and knockout animals

(2009) Benoit Viollet   Frontiers in Bioscience-Landmark

E2F1 transcription is induced by genotoxic stress through ATM/ATR activation

(2009) Abel L. Carcagno et al.   IUBMB LIFE

An E2F1-Dependent Gene Expression Program that Determines the Balance between Proliferation and Cell Death

(2008) Timothy C. Hallstrom et al.   CANCER CELL

E2F-like elements in p27Kip1promoter specifically sense deregulated E2F activity

(2008) Eiko Ozono et al.   GENES TO CELLS

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

(2008) Pekka Katajisto et al.   NATURE GENETICS