Modulation of the Mevalonate Pathway by Akt Regulates Macrophage Survival and Development of Pulmonary Fibrosis
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Modulation of the Mevalonate Pathway by Akt Regulates Macrophage Survival and Development of Pulmonary Fibrosis
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 52, Pages 36204-36219
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-11-07
DOI
10.1074/jbc.m114.593285
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tumor Necrosis Factor-α Accelerates the Resolution of Established Pulmonary Fibrosis in Mice by Targeting Profibrotic Lung Macrophages
- (2014) Elizabeth F. Redente et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus
- (2013) Ravid Shechter et al. IMMUNITY
- Accelerated Development of Pulmonary Fibrosis via Cu,Zn-superoxide Dismutase-induced Alternative Activation of Macrophages
- (2013) Chao He et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Rac1/Cdc42 GTPase-Specific Small Molecule Inhibitor Suppresses Growth of Primary Human Prostate Cancer Xenografts and Prolongs Survival in Mice
- (2013) Karin Zins et al. PLoS One
- Mitochondrial Reactive Oxygen Species Regulate Transforming Growth Factor-β Signaling
- (2012) Manu Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Statins in the prevention of dementia and Alzheimer's disease: A meta-analysis of observational studies and an assessment of confounding
- (2012) William B. Wong et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
- (2012) A. Arranz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Isoprenoid biosynthesis is required for miRNA function and affects membrane association of ARGONAUTE 1 in Arabidopsis
- (2012) P. Brodersen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphatidylinositol 3′-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1α and vascular endothelial growth factor expression
- (2011) Yan Xue et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Hepatic Akt expression correlates with advanced fibrosis in patients with chronic hepatitis C infection
- (2011) Jee-Fu Huang et al. HEPATOLOGY RESEARCH
- Thrombin Induces NF-κB Activation and IL-8/CXCL8 Expression in Lung Epithelial Cells by a Rac1-dependent PI3K/Akt Pathway
- (2011) Chien-Huang Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Cu,Zn-Superoxide Dismutase Mediates Pulmonary Fibrosis by Augmenting H2O2Generation
- (2011) Chao He et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Rac1 GTPase Import and Electron Transfer from CytochromecAre Required for Pulmonary Fibrosis
- (2011) Heather L. Osborn-Heaford et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bisphosphonates Induce Autophagy by Depleting Geranylgeranyl Diphosphate
- (2011) B. M. Wasko et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Akt1 deletion prevents lung tumorigenesis by mutant K-ras
- (2011) M C Hollander et al. ONCOGENE
- Alternatively activated alveolar macrophages in pulmonary fibrosis—mediator production and intracellular signal transduction
- (2010) Dmitri V. Pechkovsky et al. CLINICAL IMMUNOLOGY
- Rac1-mediated Mitochondrial H2O2Generation RegulatesMMP-9Gene Expression in Macrophages via Inhibition of SP-1 and AP-1
- (2010) Shubha Murthy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of PI3K by PX-866 Prevents Transforming Growth Factor-α–Induced Pulmonary Fibrosis
- (2009) Timothy D. Le Cras et al. AMERICAN JOURNAL OF PATHOLOGY
- Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis
- (2009) Shubha Murthy et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Phosphatidylinositol-3-Kinase/Akt Regulates Bleomycin-Induced Fibroblast Proliferation and Collagen Production
- (2009) Yongju Lu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The phenotype of murine wound macrophages
- (2009) Jean M. Daley et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Blockade of Protein Geranylgeranylation Inhibits Cdk2-Dependent p27Kip1 Phosphorylation on Thr187 and Accumulates p27Kip1 in the Nucleus: Implications for Breast Cancer Therapy
- (2009) A. Kazi et al. MOLECULAR AND CELLULAR BIOLOGY
- Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis
- (2008) G. Carmona et al. BLOOD
- Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development
- (2008) F. Guo et al. BLOOD
- HMG-CoA reductase inhibition induces IL-1 release through Rac1/PI3K/PKB-dependent caspase-1 activation
- (2008) L. M. Kuijk et al. BLOOD
- AKT and Oxidative Stress Team Up to Kill Cancer Cells
- (2008) Ignacio Dolado et al. CANCER CELL
- Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis
- (2008) Veronique Nogueira et al. CANCER CELL
- Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis
- (2008) Hong Xia et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A quantitative atlas of mitotic phosphorylation
- (2008) N. Dephoure et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now