Structural Determinants of Phosphatidylinositol 4,5-Bisphosphate (PIP2) Regulation of BK Channel Activity through the RCK1 Ca2+Coordination Site

SLO-2 isoforms with unique Ca2+- and voltage-dependence characteristics confer sensitivity to hypoxia inC. elegans

(2013) Zhe Zhang et al.   Channels

The phosphoinositide sensitivity of the KVchannel family

(2013) Martin Kruse et al.   Channels

Inter-α/β subunits coupling mediating pre-inactivation and augmented activation of BKCa(β2)

(2013) Panpan Hou et al.   Scientific Reports

Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2on Shaker K+Channels

(2012) Fayal Abderemane-Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of voltage-gated potassium channels by PI(4,5)P2

(2012) Martin Kruse et al.   JOURNAL OF GENERAL PHYSIOLOGY

PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker

(2012) A. A. Rodriguez-Menchaca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Block of mouse Slo1 and Slo3 K+channels by CTX, IbTX, TEA, 4-AP and quinidine

(2010) Qiong-Yao Tang et al.   Channels

Phosphatidylinositol 4,5-Bisphosphate Activates Slo3 Currents and Its Hydrolysis Underlies the Epidermal Growth Factor-induced Current Inhibition

(2010) Qiong-Yao Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycine311, a determinant of paxilline block in BK channels: a novel bend in the BK S6 helix

(2010) Yu Zhou et al.   JOURNAL OF GENERAL PHYSIOLOGY

Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+

(2010) Christopher Shelley et al.   JOURNAL OF GENERAL PHYSIOLOGY

The RCK2 Domain Uses a Coordination Site Present in Kir Channels to Confer Sodium Sensitivity to Slo2.2 Channels

(2010) Z. Zhang et al.   JOURNAL OF NEUROSCIENCE

Structure of the gating ring from the human large-conductance Ca2+-gated K+ channel

(2010) Yunkun Wu et al.   NATURE

An Epilepsy/Dyskinesia-Associated Mutation Enhances BK Channel Activation by Potentiating Ca2+ Sensing

(2010) Junqiu Yang et al.   NEURON

Channelopathies linked to plasma membrane phosphoinositides

(2010) Diomedes E. Logothetis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Ion sensing in the RCK1 domain of BK channels

(2010) G. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Human BK Channel Ca2+-Activation Apparatus at 3.0 A Resolution

(2010) P. Yuan et al.   SCIENCE

BK channel activation: structural and functional insights

(2010) Urvi S. Lee et al.   TRENDS IN NEUROSCIENCES

Role of KCNMA1gene in breast cancer invasion and metastasis to brain

(2009) Divya Khaitan et al.   BMC CANCER

Closed-channel block of BK potassium channels by bbTBA requires partial activation

(2009) Qiong-Yao Tang et al.   JOURNAL OF GENERAL PHYSIOLOGY

PIP2 Is a Necessary Cofactor for Ion Channel Function: How and Why?

(2008) Byung-Chang Suh et al.   Annual Review of Biophysics

An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity

(2008) Max A. Seibold et al.   HUMAN MOLECULAR GENETICS

Direct Regulation of BK Channels by Phosphatidylinositol 4,5-Bisphosphate as a Novel Signaling Pathway

(2008) Thirumalini Vaithianathan et al.   JOURNAL OF GENERAL PHYSIOLOGY

Genetic variation in the KCNMA1 potassium channel α subunit as risk factor for severe essential hypertension and myocardial infarction

(2008) Marta Tomás et al.   JOURNAL OF HYPERTENSION

The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes

(2008) Trine Nielsen et al.   JOURNAL OF HYPERTENSION

The KCNMB1 E65K variant is associated with reduced central pulse pressure in the community-based Framingham Offspring Cohort

(2008) Alyson Kelley-Hedgepeth et al.   JOURNAL OF HYPERTENSION