LGR4/GPR48 Inactivation Leads to Aniridia-Genitourinary Anomalies-Mental Retardation Syndrome Defects

Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells

(2013) Shinzo Yamamoto et al.   CARCINOGENESIS

Lgr4-mediated Wnt/ -catenin signaling in peritubular myoid cells is essential for spermatogenesis

(2013) Y. Qian et al.   DEVELOPMENT

Lgr4/Gpr48 Negatively Regulates TLR2/4-associated Pattern Recognition and Innate Immunity by Targeting CD14 Expression

(2013) Bing Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multi-functional norrin is a ligand for the LGR4 receptor

(2013) C. Deng et al.   JOURNAL OF CELL SCIENCE

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

(2013) Unnur Styrkarsdottir et al.   NATURE

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation

(2013) Weijia Luo et al.   STEM CELLS

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2

(2013) Ying Wang et al.   STEM CELLS

Clenbuterol upregulates histone demethylase JHDM2a via the β2-adrenoceptor/cAMP/PKA/p-CREB signaling pathway

(2012) Yang Li et al.   CELLULAR SIGNALLING

Epigenetic regulation of olfactory receptor gene expression by the Myb-MuvB/dREAM complex

(2012) C. K. Sim et al.   GENES & DEVELOPMENT

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5

(2012) Heinz Ruffner et al.   PLoS One

Chemokine Gene Silencing in Decidual Stromal Cells Limits T Cell Access to the Maternal-Fetal Interface

(2012) P. Nancy et al.   SCIENCE

11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity

(2011) Marwan Shinawi et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells

(2011) Fábio Pereira et al.   HUMAN MOLECULAR GENETICS

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Embryonic Kidney Branching Morphogenesis and Glomerular Development by KISS1 Receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 Expression

(2010) Tingfang Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping and expression analyses during porcine foetal muscle development of 12 genes involved in histone modifications

(2009) Y. B. Peng et al.   ANIMAL GENETICS

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

(2009) J. Luo et al.   DEVELOPMENT

Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism

(2008) S. Xu et al.   CYTOGENETIC AND GENOME RESEARCH

Ovarian development in mice requires the GATA4-FOG2 transcription complex

(2008) N. L. Manuylov et al.   DEVELOPMENT

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b

(2008) Jin He et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

(2008) Joan C. Han et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2

(2008) J. Weng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA