Biosynthesis and Expression of a Disintegrin-like and Metalloproteinase Domain with Thrombospondin-1 Repeats-15

Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves

(2013) Loren E. Dupuis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Anti-angiogenic properties of ADAMTS-4 in vitro

(2012) Yi-Ping Hsu et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Versican Processing by a Disintegrin-like and Metalloproteinase Domain with Thrombospondin-1 Repeats Proteinases-5 and -15 Facilitates Myoblast Fusion

(2012) Nicole Stupka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease

(2011) Loren E. Dupuis et al.   DEVELOPMENTAL BIOLOGY

Emerging roles for ADAMTS5 during development and disease

(2011) Christopher Kintakas et al.   MATRIX BIOLOGY

ADAMTS9 Is a Cell-Autonomously Acting, Anti-Angiogenic Metalloprotease Expressed by Microvascular Endothelial Cells

(2010) Bon-Hun Koo et al.   AMERICAN JOURNAL OF PATHOLOGY

Androgen RegulatesADAMTS15Gene Expression in Prostate Cancer Cells

(2010) Chidi N. Molokwu et al.   CANCER INVESTIGATION

Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis

(2010) P. H. Y. Lo et al.   CANCER RESEARCH

Versican induces a pro-metastatic ovarian cancer cell behavior which can be inhibited by small hyaluronan oligosaccharides

(2010) Miranda P. Ween et al.   CLINICAL & EXPERIMENTAL METASTASIS

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation

(2010) H. Enomoto et al.   DEVELOPMENT

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies

(2010) Christine B. Kern et al.   MATRIX BIOLOGY

Genetic Inactivation of ADAMTS15 Metalloprotease in Human Colorectal Cancer

(2009) C. G. Viloria et al.   CANCER RESEARCH

ADAMTS Metalloproteases Generate Active Versican Fragments that Regulate Interdigital Web Regression

(2009) Daniel R. McCulloch et al.   DEVELOPMENTAL CELL

Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues

(2009) Daniel R. McCulloch et al.   GENE EXPRESSION PATTERNS

Versican overexpression in human breast cancer lesions: Known and new isoforms for stromal tumor targeting

(2009) Philippe Kischel et al.   INTERNATIONAL JOURNAL OF CANCER

A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms

(2009) Suneel S. Apte   JOURNAL OF BIOLOGICAL CHEMISTRY

10mM glucosamine prevents activation of proADAMTS5 (aggrecanase-2) in transfected cells by interference with post-translational modification of furin

(2009) D.R. McCulloch et al.   OSTEOARTHRITIS AND CARTILAGE

Proprotein convertase activation of aggrecanases in cartilage in situ

(2008) Anne-Marie Malfait et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterization of proADAMTS5 processing by proprotein convertases

(2008) Jean-Michel Longpré et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Secreted Metalloprotease ADAMTS20 Is Required for Melanoblast Survival

(2008) Debra L. Silver et al.   PLoS Genetics